Anti-NFRKB antibody (463-512) (STJ94454)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenThe antiserum was produced against synthesized peptide derived from human NFRKB. AA range:463-512
General Information
| Short Description | Rabbit polyclonal anti-Nuclear factor related to kappa-B-binding protein (463-512) for use in WB, ELISA and IHC in Human, Mouse and Monkey samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA/IHC |
| Host | Rabbit |
| Reactivity | Human/Mouse/Monkey |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000IHC-p 1:50-300ELISA 2000-20000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | NFRKB |
| Gene ID | 4798 |
| Uniprot ID | NFRKB_HUMAN |
| Immunogen | The antiserum was produced against synthesized peptide derived from human NFRKB. AA range:463-512 |
| Immunogen Region | 463-512 |
| Specificity | NFR Kappa B Polyclonal Antibody detects endogenous levels of NFR Kappa B protein. |
Additional Info
| Tissue Specificity | Expressed in thymus, brain, testes, spleen and liver. |
| Function | Binds to the DNA consensus sequence 5'-GGGGAATCTCC-3'. Putative regulatory component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair. Modulates the deubiquitinase activity of UCHL5 in the INO80 complex. |
| Protein Name | Nuclear Factor Related To Kappa-B-Binding ProteinDna-Binding Protein R Kappa-BIno80 Complex Subunit G |
| Database Links | Reactome: R-HSA-5689603Reactome: R-HSA-5696394 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Nuclear Factor Related To Kappa-B-Binding Protein antibodyAnti-Dna-Binding Protein R Kappa-B antibodyAnti-Ino80 Complex Subunit G antibodyAnti-NFRKB antibodyAnti-INO80G antibody |
Information sourced from Uniprot.org