| Short Description : | Rabbit polyclonal anti-NFAT activation molecule 1 (30-110 aa) for use in WB and ELISA in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/ELISA |
| Host: | Rabbit |
| Reactivity: | Human/Rat/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | 1 mg/mL |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range: | WB 1:500-2000ELISA 1:5000-20000 |
| Formulation: | Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | NFAM1 |
| Gene ID: | 150372 |
| Uniprot ID: | NFAM1_HUMAN |
| Immunogen: | Synthesized peptide derived from the human protein at the amino acid range 30-110 |
| Immunogen Region: | 30-110 aa |
| Specificity: | NFAM1 Polyclonal Antibody detects endogenous levels of protein. |
| Post Translational Modifications | N-glycosylated. |
| Function | May function in immune system as a receptor which activates via the calcineurin/NFAT-signaling pathway the downstream cytokine gene promoters. Activates the transcription of IL-13 and TNF-alpha promoters. May be involved in the regulation of B-cell, but not T-cell, development. Overexpression activates downstream effectors without ligand binding or antibody cross-linking. |
| Protein Name | Nfat Activation Molecule 1Calcineurin/Nfat-Activating Itam-Containing ProteinNfat-Activating Protein With Itam Motif 1 |
| Database Links | Reactome: R-HSA-6798695 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane ProteinPartially Recruited To Lipid Rafts Upon Bcr Stimulation |
| Alternative Antibody Names | Anti-Nfat Activation Molecule 1 antibodyAnti-Calcineurin/Nfat-Activating Itam-Containing Protein antibodyAnti-Nfat-Activating Protein With Itam Motif 1 antibodyAnti-NFAM1 antibodyAnti-CNAIP antibody |
Information sourced from Uniprot.org
