Anti-Neuroligin 3 antibody (Internal) (STJ71395)
SPECIFICATIONS
ClonalityPolyclonal
HostGoat
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Goat polyclonal antibody anti-Neuroligin 3 (Internal) is suitable for use in ELISA and Western Blot research applications. |
| Applications | Pep-ELISA/WB |
| Host | Goat |
| Reactivity | Human/Mouse/Rat/Dog |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.5 mg/mL |
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Dilution Range | Peptide ELISA: antibody detection limit dilution 1:16000.WB: Approx. 85-90kDa band observed in Human Brain (Amygdala) lysates (calculated MW of 91.6kDa according to NP_061850.2). In transfected HEK293 transiently expressing Neuregulin3 a band of |
| Formulation | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Storage Instruction | Store at-20°C on receipt and minimise freeze-thaw cycles. |
Target Information
| Gene Symbol | NLGN3 |
| Gene ID | 54413 |
| Uniprot ID | NLGN3_HUMAN |
| Accession Number | NP_061850.2 |
| Immunogen Region | Internal |
| Immunogen Sequence | RKDKRRQEPLRQPS |
Additional Info
| Function | Cell surface protein involved in cell-cell-interactions via its interactions with neurexin family members. Plays a role in synapse function and synaptic signal transmission, and may mediate its effects by clustering other synaptic proteins. May promote the initial formation of synapses, but is not essential for this. May also play a role in glia-glia or glia-neuron interactions in the developing peripheral nervous system. |
| Protein Name | Neuroligin-3Gliotactin Homolog |
| Database Links | Reactome: R-HSA-6794361 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane ProteinSynapseDetected At Both Glutamatergic And Gabaergic Synapses |
| Alternative Antibody Names | Anti-Neuroligin-3 antibodyAnti-Gliotactin Homolog antibodyAnti-NLGN3 antibodyAnti-KIAA1480 antibodyAnti-NL3 antibody |
Information sourced from Uniprot.org