| Host: | Rabbit |
| Applications: | WB/IP |
| Reactivity: | Human/Mouse/Rat/Hamster |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit monoclonal anti-Neurokinin 1 Receptor for use in WB and IP in Human, Mouse, Rat and Hamster samples. Datasheet included with dilution recommendations, and related reagents. |
| Clonality : | Monoclonal |
| Clone ID : | R05-3D1 |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | 50mM Tris-Glycine (pH 7.4) , 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA |
| Purification: | Affinity Purified |
| Concentration: | 0.3 mg/mL |
| Dilution Range: | WB 1:500-1:1000IP 1:20 |
| Storage Instruction: | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
| Gene Symbol: | TACR1 |
| Gene ID: | 6869 |
| Uniprot ID: | NK1R_HUMAN |
| Immunogen: | A synthetic peptide of human Neurokinin 1 Receptor |
| Function | This is a receptor for the tachykinin neuropeptide substance P. It is probably associated with G proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of affinity of this receptor to tachykinins is: substance P > substance K > neuromedin-K. |
| Protein Name | Substance-P ReceptorSprNk-1 ReceptorNk-1rTachykinin Receptor 1 |
| Database Links | Reactome: R-HSA-380095Reactome: R-HSA-416476Reactome: R-HSA-8856825Reactome: R-HSA-8856828 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Substance-P Receptor antibodyAnti-Spr antibodyAnti-Nk-1 Receptor antibodyAnti-Nk-1r antibodyAnti-Tachykinin Receptor 1 antibodyAnti-TACR1 antibodyAnti-NK1R antibodyAnti-TAC1R antibody |
Information sourced from Uniprot.org