| Host: | Chicken |
| Applications: | IHC/ICC/WB |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Chicken polyclonal anti-Neurofilament Medium Chain (C-Term) for use in IHC, ICC and WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgY |
| Formulation: | Phosphate-buffered (10 mM) isotonic (0.9%, w/v) saline (PBS" pH 7.2) with bovine serum albumin (BSA, 0.5%) added to prevent absorption to the plastic and sodium azide (0.02%, w/v) added as a preservative" |
| Purification: | IgY Fraction |
| Concentration: | 2 mg/mL |
| Dilution Range: | WB 1:1000-1:2000IHC 1:1000-1:2000ICC 1:1000-1:2000 |
| Storage Instruction: | Store at 4°C in the dark. Under these conditions, the antibodies should have a shelf life of at least twelve months, provided they remain sterile. For longer term storage, aliquot and freeze to avoid freeze-thaw of the antibody. |
| Gene Symbol: | NEFM |
| Gene ID: | 4741 |
| Uniprot ID: | NFM_HUMAN |
| Immunogen Region: | C-Term |
| Immunogen: | Recombinant construct containing the C-terminus of the human sequence expressed in Escherichia coli |
| Immunogen Sequence: | Human |
| Function | Neurofilaments usually contain three intermediate filament proteins: NEFL, NEFM, and NEFH which are involved in the maintenance of neuronal caliber. May additionally cooperate with the neuronal intermediate filament proteins PRPH and INA to form neuronal filamentous networks. |
| Protein Name | Neurofilament Medium PolypeptideNf-M160 Kda Neurofilament ProteinNeurofilament 3Neurofilament Triplet M Protein |
| Database Links | |
| Cellular Localisation | CytoplasmCytoskeletonCell ProjectionAxon |
| Alternative Antibody Names | Anti-Neurofilament Medium Polypeptide antibodyAnti-Nf-M antibodyAnti-160 Kda Neurofilament Protein antibodyAnti-Neurofilament 3 antibodyAnti-Neurofilament Triplet M Protein antibodyAnti-NEFM antibodyAnti-NEF3 antibodyAnti-NFM antibody |
Information sourced from Uniprot.org