| Host: | Chicken |
| Applications: | IHC/ICC/WB |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Chicken polyclonal anti-Neurofilament Heavy Chain for use in IHC, ICC and WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgY |
| Formulation: | Phosphate-buffered (10 mM) isotonic (0.9%, w/v) saline (PBS" pH 7.2) with bovine serum albumin (BSA, 0.5%) added to prevent absorption to the plastic and sodium azide (0.02%, w/v) added as a preservative" |
| Purification: | IgY Fraction |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:5000-1:10, 000IHC 1:2000-1:5000ICC 1:2000-1:5000 |
| Storage Instruction: | Store at 4°C in the dark. Under these conditions, the antibodies should have a shelf life of at least twelve months, provided they remain sterile. For longer term storage, aliquot and freeze to avoid freeze-thaw of the antibody. |
| Gene Symbol: | NEFH |
| Gene ID: | 4744 |
| Uniprot ID: | NFH_HUMAN |
| Immunogen: | Native NF-H purified from bovine spinal cord |
| Immunogen Sequence: | Cow |
| Function | Neurofilaments usually contain three intermediate filament proteins: NEFL, NEFM, and NEFH which are involved in the maintenance of neuronal caliber. NEFH has an important function in mature axons that is not subserved by the two smaller NF proteins. May additionally cooperate with the neuronal intermediate filament proteins PRPH and INA to form neuronal filamentous networks. |
| Protein Name | Neurofilament Heavy PolypeptideNf-H200 Kda Neurofilament ProteinNeurofilament Triplet H Protein |
| Database Links | |
| Cellular Localisation | CytoplasmCytoskeletonCell ProjectionAxon |
| Alternative Antibody Names | Anti-Neurofilament Heavy Polypeptide antibodyAnti-Nf-H antibodyAnti-200 Kda Neurofilament Protein antibodyAnti-Neurofilament Triplet H Protein antibodyAnti-NEFH antibodyAnti-KIAA0845 antibodyAnti-NFH antibody |
Information sourced from Uniprot.org
