| Function | Transcriptional regulator implicated in neuronal determination. Mediates calcium-dependent transcription activation by binding to E box-containing promoter. Critical factor essential for the repression of the genetic program for neuronal differentiation.prevents the formation of synaptic vesicle clustering at active zone to the presynaptic membrane in postmitotic neurons. Induces transcription of ZEB1, which in turn represses neuronal differentiation by down-regulating REST expression. Plays a role in the establishment and maturation of thalamocortical connections.involved in the segregation of thalamic afferents into distinct barrel domains within layer VI of the somatosensory cortex. Involved in the development of the cerebellar and hippocampal granular neurons, neurons in the basolateral nucleus of amygdala and the hypothalamic-pituitary axis. Associates with chromatin to the DPYSL3 E box-containing promoter. |
| Protein Name | Neurogenic Differentiation Factor 2Neurod2Class A Basic Helix-Loop-Helix Protein 1Bhlha1Neurod-Related FactorNdrf |
| Database Links | |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Neurogenic Differentiation Factor 2 antibodyAnti-Neurod2 antibodyAnti-Class A Basic Helix-Loop-Helix Protein 1 antibodyAnti-Bhlha1 antibodyAnti-Neurod-Related Factor antibodyAnti-Ndrf antibodyAnti-NEUROD2 antibodyAnti-BHLHA1 antibodyAnti-NDRF antibody |
Information sourced from Uniprot.org
