• Immunohistochemistry analysis of paraffin-embedded human heart tissue, using NEURL2 Antibody. The picture on the right is blocked with the synthesized peptide.
  • Western blot analysis of lysates from Jurkat, COLO, and K562 cells, using NEURL2 Antibody. The lane on the right is blocked with the synthesized peptide.
  • Western blot analysis of various cells using Neuralized-2 Polyclonal Antibody

Anti-NEURL2 antibody (99-148) (STJ94418)

SKU:
STJ94418

£46.00 - £226.00
Current Stock:
Host: Rabbit
Applications: WB/IHC/IF/ELISA
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Neuralized-like protein 2 (99-148) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-1:2000
IHC 1:100-1:300
ELISA 1:40000
IF 1:50-200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: NEURL2
Gene ID: 140825
Uniprot ID: NEUL2_HUMAN
Immunogen Region: 99-148
Specificity: Neuralized-2 Polyclonal Antibody detects endogenous levels of Neuralized-2 protein.
Immunogen: The antiserum was produced against synthesized peptide derived from human NEURL2. AA range:99-148
Tissue Specificity Expressed specifically in skeletal and cardiac muscles.
Function Plays an important role in the process of myofiber differentiation and maturation. Probable substrate-recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex, which mediates the ubiquitination of proteins. Probably contributes to catalysis through recognition and positioning of the substrate and the ubiquitin-conjugating enzyme. During myogenesis, controls the ubiquitination and degradation of the specific pool of CTNNB1/beta-catenin located at the sarcolemma.
Protein Name Neuralized-Like Protein 2
Database Links Reactome: R-HSA-8951664
Cellular Localisation Cytoplasm
Alternative Antibody Names Anti-Neuralized-Like Protein 2 antibody
Anti-NEURL2 antibody
Anti-C20orf163 antibody

Information sourced from Uniprot.org

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