Anti-Nestin antibody (STJA0033155)

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STJA0033155
£214.50 - £308.50
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Short Description :Mouse monoclonal anti-Nestin for use in WB in Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents.
Applications:WB
Host:Mouse
Reactivity:Mouse/Rat
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality :Monoclonal
Conjugation:Unconjugated
Purification:Affinity Chromatography
Dilution Range:WB-1:500-1:1000
Formulation:Liquid in PBS, Glycerol and BSA
Storage Instruction:Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles.
Gene Symbol:NES
Gene ID:10763
Uniprot ID:NEST_HUMAN
Immunogen:Peptide
Tissue Specificity CNS stem cells.
Post Translational Modifications Constitutively phosphorylated. This increases during mitosis when the cytoplasmic intermediate filament network is reorganized.
Function Required for brain and eye development. Promotes the disassembly of phosphorylated vimentin intermediate filaments (IF) during mitosis and may play a role in the trafficking and distribution of IF proteins and other cellular factors to daughter cells during progenitor cell division. Required for survival, renewal and mitogen-stimulated proliferation of neural progenitor cells.
Protein Name Nestin
Database Links
Cellular Localisation
Alternative Antibody Names Anti-Nestin antibody
Anti-NES antibody
Anti-Nbla00170 antibody

Information sourced from Uniprot.org