Host: |
Mouse |
Applications: |
IHC/IF |
Reactivity: |
Human |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Mouse monoclonal antibody anti-Nestin is suitable for use in Immunohistochemistry and Immunofluorescence research applications. |
Clonality: |
Monoclonal |
Clone ID: |
SM4950 |
Conjugation: |
Unconjugated |
Isotype: |
IgG2bk |
Formulation: |
PBS with 0.02% sodium azide, 100 Mu g/ml BSA and 50% glycerol. |
Purification: |
Affinity purification |
Dilution Range: |
IHC/IF (H) 1:500-1:1000 |
Storage Instruction: |
Store at-20C for up to one year, and avoid repeated freeze-thaw cycles. |
Gene Symbol: |
NES |
Gene ID: |
10763 |
Uniprot ID: |
NEST_HUMAN |
Immunogen: |
Recombinant protein corresponding to Human Nestin |
Post Translational Modifications | Constitutively phosphorylated. This increases during mitosis when the cytoplasmic intermediate filament network is reorganized. |
Function | Required for brain and eye development. Promotes the disassembly of phosphorylated vimentin intermediate filaments (IF) during mitosis and may play a role in the trafficking and distribution of IF proteins and other cellular factors to daughter cells during progenitor cell division. Required for survival, renewal and mitogen-stimulated proliferation of neural progenitor cells. |
Protein Name | Nestin |
Alternative Antibody Names | Anti-Nestin antibodyAnti-NES antibodyAnti-Nbla00170 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance