Anti-Nestin antibody [SM4950] (STJA0004950)

SKU:
STJA0004950

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Host: Mouse
Applications: IHC/IF
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Mouse monoclonal antibody anti-Nestin is suitable for use in Immunohistochemistry and Immunofluorescence research applications.
Clonality: Monoclonal
Clone ID: SM4950
Conjugation: Unconjugated
Isotype: IgG2bk
Formulation: PBS with 0.02% sodium azide, 100 Mu g/ml BSA and 50% glycerol.
Purification: Affinity purification
Dilution Range: IHC/IF (H) 1:500-1:1000
Storage Instruction: Store at-20C for up to one year, and avoid repeated freeze-thaw cycles.
Gene Symbol: NES
Gene ID: 10763
Uniprot ID: NEST_HUMAN
Immunogen: Recombinant protein corresponding to Human Nestin
Post Translational Modifications Constitutively phosphorylated. This increases during mitosis when the cytoplasmic intermediate filament network is reorganized.
Function Required for brain and eye development. Promotes the disassembly of phosphorylated vimentin intermediate filaments (IF) during mitosis and may play a role in the trafficking and distribution of IF proteins and other cellular factors to daughter cells during progenitor cell division. Required for survival, renewal and mitogen-stimulated proliferation of neural progenitor cells.
Protein Name Nestin
Alternative Antibody Names Anti-Nestin antibody
Anti-NES antibody
Anti-Nbla00170 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance