Anti-NENF antibody (STJA0009760)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from human Neudesin/NENF
General Information
| Short Description | Rabbit polyclonal anti-Neudesin for use in WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | NENF |
| Gene ID | 29937 |
| Uniprot ID | NENF_HUMAN |
| Immunogen | Synthesized peptide derived from human Neudesin/NENF |
| Specificity | This antibody detects endogenous levels of Neudesin/NENF at Human, Mouse, Rat |
Additional Info
| Function | Acts as a neurotrophic factor in postnatal mature neurons enhancing neuronal survival. Promotes cell proliferation and neurogenesis in undifferentiated neural progenitor cells at the embryonic stage and inhibits differentiation of astrocytes. Its neurotrophic activity is exerted via MAPK1/ERK2, MAPK3/ERK1 and AKT1/AKT pathways. Neurotrophic activity is enhanced by binding to heme. Also acts as an anorexigenic neurotrophic factor that contributes to energy balance. |
| Protein Name | NeudesinCell Immortalization-Related Protein 2Neuron-Derived Neurotrophic FactorProtein Gig47Secreted Protein Of Unknown FunctionSpuf Protein |
| Database Links | |
| Cellular Localisation | SecretedExtracellular SpaceMitochondrionEndoplasmic ReticulumLocalized To Mitochondria And Endoplasmic Reticulum By Pink1 And Park7 |
| Alternative Antibody Names | Anti-Neudesin antibodyAnti-Cell Immortalization-Related Protein 2 antibodyAnti-Neuron-Derived Neurotrophic Factor antibodyAnti-Protein Gig47 antibodyAnti-Secreted Protein Of Unknown Function antibodyAnti-Spuf Protein antibodyAnti-NENF antibodyAnti-CIR2 antibodyAnti-SPUF antibody |
Information sourced from Uniprot.org