Anti-NECTIN4/PVRL4 antibody [SAA0403] (STJA0027584)

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STJA0027584-100
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Short Description :Mouse monoclonal Nectin-4 antibody for use in ELISA and FC in human samples. Datasheet included with dilution recommendations, and related reagents.
Applications:ELISA/FC
Host:Mouse
Reactivity:Human
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality :Monoclonal
Clone ID :SAA0403
Isotype:IgG2ak
Conjugation:Unconjugated
Concentration:1 mg/ml
Purification:Protein A/G purified from cell culture supernatant.
Formulation:0.01M PBS, pH 7.4, 0.09% Sodium azide.
Storage Instruction:Suitable for storage at +4°C between 1-2 weeks. For longer term store at-20°C for up to 12 months.
Gene Symbol:NECTIN4
Gene ID:81607
Uniprot ID:NECT4_HUMAN
Post Translational Modifications The soluble form is produced by proteolytic cleavage at the cell surface (shedding), probably by ADAM17/TACE.
Function Seems to be involved in cell adhesion through trans-homophilic and -heterophilic interactions, the latter including specifically interactions with NECTIN1. Does not act as receptor for alpha-herpesvirus entry into cells. (Microbial infection) Acts as a receptor for measles virus.
Protein Name Nectin-4
Ig Superfamily Receptor Lnir
Nectin Cell Adhesion Molecule 4
Poliovirus Receptor-Related Protein 4 Cleaved Into - Processed Poliovirus Receptor-Related Protein 4
Database Links Reactome: R-HSA-418990
Reactome: R-HSA-420597
Cellular Localisation Cell Membrane
Single-Pass Type I Membrane Protein
Cell Junction
Adherens Junction
Colocalizes With Afdn At Cadherin-Based Adherens Junctions
Processed Poliovirus Receptor-Related Protein 4: Secreted
The Secreted Form Is Found In Breast Tumor Patients
Alternative Antibody Names Anti-Nectin-4 antibody
Anti-Ig Superfamily Receptor Lnir antibody
Anti-Nectin Cell Adhesion Molecule 4 antibody
Anti-Poliovirus Receptor-Related Protein 4 Cleaved Into - Processed Poliovirus Receptor-Related Protein 4 antibody
Anti-NECTIN4 antibody
Anti-LNIR antibody
Anti-PRR4 antibody
Anti-PVRL4 antibody

Information sourced from Uniprot.org