| Short Description : | Rabbit polyclonal NDUFAF2 (1-169) antibody for use in WB, IF, ICC and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/IF/ICC/ELISA |
| Host: | Rabbit |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | Lot specific |
| Purification: | Affinity purification |
| Dilution Range: | WB:1:500-1:2000IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | NDUFAF2 |
| Gene ID: | 91942 |
| Uniprot ID: | NDUF2_HUMAN |
| Immunogen Region: | 1-169 |
| Immunogen Sequence: | MGWSQDLFRALWRSLSREVK EHVGTDQFGNKYYYIPQYKN WRGQTIREKRIVEAANKKEV DYEAGDIPTEWEAWIRRTRK TPPTMEEILKNEKHREEIKI KSQDFYEKEKLLSKETSEEL LPPPVQTQIKGHASAPYFGK EEPSVAPSSTGKTFQPGSWM PRDGKSHNQ |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-169 of human NDUFAF2 (NP_777549.1). |
| Tissue Specificity | Highly expressed in ESCC cells. Also expressed in heart, skeletal muscle, liver, and in fibroblasts. |
| Function | Acts as a molecular chaperone for mitochondrial complex I assembly. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. Is involved in the initial steps of cilia formation, including removal of CP110 from the mother centrioles, docking of membrane vesicles to the mother centrioles, and establishment of the transition zone. |
| Protein Name | Nadh Dehydrogenase Ubiquinone 1 Alpha Subcomplex Assembly Factor 2B17.2-LikeB17.2lMimitinMyc-Induced Mitochondrial ProteinMmtnNdufa12-Like Protein |
| Database Links | Reactome: R-HSA-6799198 |
| Cellular Localisation | Mitochondrion |
| Alternative Antibody Names | Anti-Nadh Dehydrogenase Ubiquinone 1 Alpha Subcomplex Assembly Factor 2 antibodyAnti-B17.2-Like antibodyAnti-B17.2l antibodyAnti-Mimitin antibodyAnti-Myc-Induced Mitochondrial Protein antibodyAnti-Mmtn antibodyAnti-Ndufa12-Like Protein antibodyAnti-NDUFAF2 antibodyAnti-NDUFA12L antibody |
Information sourced from Uniprot.org
