Host: |
Rabbit |
Applications: |
WB/ELISA |
Reactivity: |
Human/Mouse |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-NADH dehydrogenase 1 alpha subcomplex subunit 13 (30-110 aa) is suitable for use in Western Blot and ELISA research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Concentration: |
1 mg/mL |
Dilution Range: |
WB 1:500-2000ELISA 1:5000-20000 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
NDUFA13 |
Gene ID: |
51079 |
Uniprot ID: |
NDUAD_HUMAN |
Immunogen Region: |
30-110 aa |
Specificity: |
NDUAD Polyclonal Antibody detects endogenous levels of protein. |
Immunogen: |
Synthesized peptide derived from the human protein at the amino acid range 30-110 |
Function | Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. Involved in the interferon/all-trans-retinoic acid (IFN/RA) induced cell death. This apoptotic activity is inhibited by interaction with viral IRF1. Prevents the transactivation of STAT3 target genes. May play a role in CARD15-mediated innate mucosal responses and serve to regulate intestinal epithelial cell responses to microbes. |
Protein Name | Nadh Dehydrogenase Ubiquinone 1 Alpha Subcomplex Subunit 13Cell Death Regulatory Protein Grim-19Complex I-B16.6Ci-B16.6Gene Associated With Retinoic And Interferon-Induced Mortality 19 ProteinGrim-19Gene Associated With Retinoic And Ifn-Induced Mortality 19 ProteinNadh-Ubiquinone Oxidoreductase B16.6 Subunit |
Database Links | Reactome: R-HSA-611105Reactome: R-HSA-6799198 |
Cellular Localisation | Mitochondrion Inner MembraneSingle-Pass Membrane ProteinMatrix SideNucleusLocalizes Mainly In The MitochondrionMay Be Translocated Into The Nucleus Upon Ifn/Ra Treatment |
Alternative Antibody Names | Anti-Nadh Dehydrogenase Ubiquinone 1 Alpha Subcomplex Subunit 13 antibodyAnti-Cell Death Regulatory Protein Grim-19 antibodyAnti-Complex I-B16.6 antibodyAnti-Ci-B16.6 antibodyAnti-Gene Associated With Retinoic And Interferon-Induced Mortality 19 Protein antibodyAnti-Grim-19 antibodyAnti-Gene Associated With Retinoic And Ifn-Induced Mortality 19 Protein antibodyAnti-Nadh-Ubiquinone Oxidoreductase B16.6 Subunit antibodyAnti-NDUFA13 antibodyAnti-GRIM19 antibodyAnti-CDA016 antibodyAnti-CGI-39 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance