| Host: |
Rabbit |
| Applications: |
IHC/WB |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-NDNF (450-500 aa) is suitable for use in Immunohistochemistry and Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Lyophilised |
| Purification: |
IgG purified |
| Dilution Range: |
IHC, WB (confirmed by recombinant protein). A dilution of 1:300 to 1:2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications. |
| Storage Instruction: |
Maintain the lyophilised/reconstituted antibodies frozen at-20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, Glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles. |
| Gene Symbol: |
NDNF |
| Gene ID: |
79625 |
| Uniprot ID: |
NDNF_HUMAN |
| Immunogen Region: |
450-500 aa |
| Specificity: |
Specific for NDNF. |
| Immunogen: |
A synthetic peptide from aa region 450-500 of human NDNF conjugated to blue carrier protein was used as the antigen. |
| Post Translational Modifications | O-glycosylated.contains heparan sulfate and chondroitin sulfate. N-glycosylated. |
| Function | Secretory protein that plays a role in various cellular processes. Acts as a chemorepellent acting on gonadotropin-releasing hormone (GnRH) expressing neurons regulating their migration to the hypothalamus. Also promotes neuron migration, growth and survival as well as neurite outgrowth and is involved in the development of the olfactory system. May also act through the regulation of growth factors activity and downstream signaling. Also regulates extracellular matrix assembly and cell adhesiveness. Promotes endothelial cell survival, vessel formation and plays an important role in the process of revascularization through NOS3-dependent mechanisms. |
| Protein Name | Protein NdnfNeuron-Derived Neurotrophic Factor |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Protein Ndnf antibodyAnti-Neuron-Derived Neurotrophic Factor antibodyAnti-NDNF antibodyAnti-C4orf31 antibodyAnti-UNQ2748 antibodyAnti-PRO6487 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
