Anti-NDC1 antibody (340-530) (STJ119769)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal NDC1 (340-530) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.09% Sodium Azide, 50% Glycerol, pH7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | NDC1 |
| Gene ID | 55706 |
| Uniprot ID | NDC1_HUMAN |
| Immunogen Region | 340-530 |
| Immunogen Sequence | QYSPSRRQEVFSLSQPGGHP HNWTAISRECLNLLNGMTQK LILYQEAAATNGRVSSSYPV EPKKLNSPEETAFQTPKSSQ MPRPSVPPLVKTSLFSSKLS TPDVVSPFGTPFGSSVMNRM AGIFDVNTCYGSPQSPQLIR RGPRLWTSASDQQMTEFSNP SPSTSISAEGKTMRQPSVIY SWIQNKREQIK |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 340-530 of human NDC1 (NP_060557.3). |
Additional Info
| Function | Component of the nuclear pore complex (NPC), which plays a key role in de novo assembly and insertion of NPC in the nuclear envelope. Required for NPC and nuclear envelope assembly, possibly by forming a link between the nuclear envelope membrane and soluble nucleoporins, thereby anchoring the NPC in the membrane. |
| Protein Name | Nucleoporin Ndc1Hndc1Transmembrane Protein 48 |
| Database Links | Reactome: R-HSA-1169408Reactome: R-HSA-159227Reactome: R-HSA-159230Reactome: R-HSA-159231Reactome: R-HSA-159236Reactome: R-HSA-165054Reactome: R-HSA-168271Reactome: R-HSA-168276Reactome: R-HSA-168325Reactome: R-HSA-168333Reactome: R-HSA-170822Reactome: R-HSA-180746Reactome: R-HSA-180910Reactome: R-HSA-191859Reactome: R-HSA-3108214Reactome: R-HSA-3232142Reactome: R-HSA-3301854Reactome: R-HSA-3371453Reactome: R-HSA-4085377Reactome: R-HSA-4551638Reactome: R-HSA-4570464Reactome: R-HSA-4615885Reactome: R-HSA-5578749Reactome: R-HSA-5619107Reactome: R-HSA-6784531Reactome: R-HSA-9609690Reactome: R-HSA-9610379Reactome: R-HSA-9615933Reactome: R-HSA-9705671 |
| Cellular Localisation | NucleusNuclear Pore ComplexNucleus MembraneMulti-Pass Membrane ProteinCentral Core Structure Of The Nuclear Pore Complex |
| Alternative Antibody Names | Anti-Nucleoporin Ndc1 antibodyAnti-Hndc1 antibodyAnti-Transmembrane Protein 48 antibodyAnti-NDC1 antibodyAnti-TMEM48 antibody |
Information sourced from Uniprot.org