Western blot analysis of the lysates from K562 cells using NCR3 antibody.

Anti-NCR3 antibody (104-153) (STJ94500)

SKU:
STJ94500
£48.00 - £252.00
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Host: Rabbit
Applications: WB/ELISA
Reactivity: Human/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Rabbit polyclonal antibody anti-Natural cytotoxicity triggering receptor 3 (104-153) is suitable for use in Western Blot and ELISA research applications.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-1:2000
ELISA 1:40000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: NCR3
Gene ID: 259197
Uniprot ID: NCTR3_HUMAN
Immunogen Region: 104-153
Specificity: NKp30 Polyclonal Antibody detects endogenous levels of NKp30 protein.
Immunogen: The antiserum was produced against synthesized peptide derived from human NCR3. AA range:104-153
Tissue Specificity Selectively expressed by all resting and activated NK cells and weakly expressed in spleen.
Function Cell membrane receptor of natural killer/NK cells that is activated by binding of extracellular ligands including BAG6 and NCR3LG1. Stimulates NK cells cytotoxicity toward neighboring cells producing these ligands. It controls, for instance, NK cells cytotoxicity against tumor cells. Engagement of NCR3 by BAG6 also promotes myeloid dendritic cells (DC) maturation, both through killing DCs that did not acquire a mature phenotype, and inducing the release by NK cells of TNFA and IFNG which promote DC maturation.
Protein Name Natural Cytotoxicity Triggering Receptor 3
Activating Natural Killer Receptor P30
Natural Killer Cell P30-Related Protein
Nk-P30
Nkp30
Cd Antigen Cd337
Database Links Reactome: R-HSA-198933
Cellular Localisation Cell Membrane
Single-Pass Type I Membrane Protein
Alternative Antibody Names Anti-Natural Cytotoxicity Triggering Receptor 3 antibody
Anti-Activating Natural Killer Receptor P30 antibody
Anti-Natural Killer Cell P30-Related Protein antibody
Anti-Nk-P30 antibody
Anti-Nkp30 antibody
Anti-Cd Antigen Cd337 antibody
Anti-NCR3 antibody
Anti-1C7 antibody
Anti-LY117 antibody

Information sourced from Uniprot.org

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