| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Rat/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Natural cytotoxicity triggering receptor 1 (145-194) is suitable for use in Western Blot and ELISA research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-1:2000ELISA 1:10000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | NCR1 |
| Gene ID: | 9437 |
| Uniprot ID: | NCTR1_HUMAN |
| Immunogen Region: | 145-194 |
| Specificity: | NKp46 Polyclonal Antibody detects endogenous levels of NKp46 protein. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from human NCR1. AA range:145-194 |
| Tissue Specificity | Selectively expressed by both resting and activated NK cells. |
| Post Translational Modifications | N-glycosylated. O-glycosylated. |
| Function | Cytotoxicity-activating receptor that may contribute to the increased efficiency of activated natural killer (NK) cells to mediate tumor cell lysis. |
| Protein Name | Natural Cytotoxicity Triggering Receptor 1Lymphocyte Antigen 94 HomologNk Cell-Activating ReceptorNatural Killer Cell P46-Related ProteinNk-P46Nkp46Hnkp46Cd Antigen Cd335 |
| Database Links | Reactome: R-HSA-198933 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Natural Cytotoxicity Triggering Receptor 1 antibodyAnti-Lymphocyte Antigen 94 Homolog antibodyAnti-Nk Cell-Activating Receptor antibodyAnti-Natural Killer Cell P46-Related Protein antibodyAnti-Nk-P46 antibodyAnti-Nkp46 antibodyAnti-Hnkp46 antibodyAnti-Cd Antigen Cd335 antibodyAnti-NCR1 antibodyAnti-LY94 antibody |
Information sourced from Uniprot.org