| Host: | Rabbit |
| Applications: | WB/ELISA/IHC |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Neutral cholesterol ester hydrolase 1 (8-58 aa) is suitable for use in Western Blot, ELISA and Immunohistochemistry research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-2000IHC-P 1:50-300ELISA 2000-20000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | NCEH1 |
| Gene ID: | 57552 |
| Uniprot ID: | NCEH1_HUMAN |
| Immunogen Region: | 8-58 aa |
| Specificity: | This antibody detects endogenous levels of NCEH1 at Human/Mouse/Rat |
| Immunogen: | Synthesized peptide derived from the human NCEH1 at the amino acid range 8-58 |
| Post Translational Modifications | N-glycosylated. |
| Function | Hydrolyzes 2-acetyl monoalkylglycerol ether (1-O-alkyl-2-acetyl-sn-glycerol), the penultimate precursor of the pathway for de novo synthesis of platelet-activating factor. May be responsible for the hydrolysis of cholesterol esters (such as cholesteryl (9Z-octadecenoate)) in macrophages. Also involved in organ detoxification by hydrolyzing exogenous organophosphorus compounds. May contribute to cancer pathogenesis by promoting tumor cell migration. |
| Protein Name | Neutral Cholesterol Ester Hydrolase 1NcehAcetylalkylglycerol Acetylhydrolase2-Acetyl Mage HydrolaseArylacetamide Deacetylase-Like 1 |
| Database Links | Reactome: R-HSA-8964038 |
| Cellular Localisation | Cell MembraneSingle-Pass Type Ii Membrane ProteinMicrosome |
| Alternative Antibody Names | Anti-Neutral Cholesterol Ester Hydrolase 1 antibodyAnti-Nceh antibodyAnti-Acetylalkylglycerol Acetylhydrolase antibodyAnti-2-Acetyl Mage Hydrolase antibodyAnti-Arylacetamide Deacetylase-Like 1 antibodyAnti-NCEH1 antibodyAnti-AADACL1 antibodyAnti-KIAA1363 antibody |
Information sourced from Uniprot.org