Anti-NCAN antibody (370-450) (STJ94429)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from Neurocan. at AA range: 370-450
General Information
| Short Description | Rabbit polyclonal anti-Neurocan core protein (370-450) for use in WB and IHC in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC |
| Host | Rabbit |
| Reactivity | Human/Rat/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000IHC-p 1:50-300 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | NCAN |
| Gene ID | 1463 |
| Uniprot ID | NCAN_HUMAN |
| Immunogen | Synthesized peptide derived from Neurocan. at AA range: 370-450 |
| Immunogen Region | 370-450 |
| Specificity | Neurocan Polyclonal Antibody detects endogenous levels of Neurocan protein. |
Additional Info
| Tissue Specificity | Detected in cerebrospinal fluid (at protein level). Brain. |
| Post Translational Modifications | O-glycosylated.contains chondroitin sulfate. |
| Function | May modulate neuronal adhesion and neurite growth during development by binding to neural cell adhesion molecules (NG-CAM and N-CAM). Chondroitin sulfate proteoglycan.binds to hyaluronic acid. |
| Protein Name | Neurocan Core ProteinChondroitin Sulfate Proteoglycan 3 |
| Database Links | Reactome: R-HSA-1971475Reactome: R-HSA-2022870Reactome: R-HSA-2022923Reactome: R-HSA-2024101Reactome: R-HSA-3000178Reactome: R-HSA-3560783Reactome: R-HSA-3560801Reactome: R-HSA-3595172Reactome: R-HSA-3595174Reactome: R-HSA-3595177Reactome: R-HSA-373760Reactome: R-HSA-419037Reactome: R-HSA-4420332 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Neurocan Core Protein antibodyAnti-Chondroitin Sulfate Proteoglycan 3 antibodyAnti-NCAN antibodyAnti-CSPG3 antibodyAnti-NEUR antibody |
Information sourced from Uniprot.org