| Host: |
Rabbit |
| Applications: |
WB/ELISA |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: |
Affinity purification |
| Concentration: |
Lot specific |
| Dilution Range: |
WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
NCAM1 |
| Gene ID: |
4684 |
| Uniprot ID: |
NCAM1_HUMAN |
| Immunogen Region: |
500-720 |
| Specificity: |
Recombinant fusion protein containing a sequence corresponding to amino acids 500-720 of human NCAM1 (NP_851996.2). |
| Immunogen Sequence: |
LEFILVQADTPSSPSIDQVE PYSSTAQVQFDEPEATGGVP ILKYKAEWRAVGEEVWHSKW YDAKEASMEGIVTIVGLKPE TTYAVRLAALNGKGLGEISA ASEFKTQPVQGEPSAPKLEG QMGEDGNSIKVNLIKQDDGG SPIRHYLVRYRALSSEWKPE IRLPSGSDHVMLKSLDWNAE YEVYVVAENQQGKSKAAHFV FRTSAQPTAIPANGSPTSGL S |
| Post Translational Modifications | Polysialylated at Asn-459 and Asn-488 by ST8SIA2 and ST8SIA4. Polysialylation modulates cell interactions by confering both attractive and repulsive properties that are highly regulated by ST8SIA2 and ST8SIA4. Polysialylation is formed on a-2,3-linked sialic acid of core glycans. |
| Function | This protein is a cell adhesion molecule involved in neuron-neuron adhesion, neurite fasciculation, outgrowth of neurites, etc. (Microbial infection) Acts as a receptor for rabies virus. (Microbial infection) Acts as a receptor for Zika virus. |
| Protein Name | Neural Cell Adhesion Molecule 1N-Cam-1Ncam-1Cd Antigen Cd56 |
| Database Links | Reactome: R-HSA-3000178Reactome: R-HSA-375165Reactome: R-HSA-419037Reactome: R-HSA-445144Reactome: R-HSA-5673001Reactome: R-HSA-877300 |
| Cellular Localisation | Isoform 1: Cell MembraneSingle-Pass Type I Membrane ProteinIsoform 2: Cell MembraneIsoform 3: Cell MembraneLipid-AnchorGpi-AnchorIsoform 4: Cell MembraneIsoform 5: SecretedIsoform 6: Secreted |
| Alternative Antibody Names | Anti-Neural Cell Adhesion Molecule 1 antibodyAnti-N-Cam-1 antibodyAnti-Ncam-1 antibodyAnti-Cd Antigen Cd56 antibodyAnti-NCAM1 antibodyAnti-NCAM antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
