| Host: | Mouse |
| Applications: | WB/IHC-P/FC/ELISA |
| Reactivity: | Human/Mouse/Monkey |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Mouse monoclonal anti-NCAM1 for use in WB, IHC-P, FC and ELISA in Human, Mouse and Monkey samples. Datasheet included with dilution recommendations, and related reagents. |
| Clonality : | Monoclonal |
| Clone ID : | 2L5-X2-R8 |
| Conjugation: | Unconjugated |
| Isotype: | IgG1 |
| Formulation: | Purified antibody in PBS with 0.05% sodium azide |
| Purification: | Affinity Purified |
| Dilution Range: | WB 1:500-1:1000IHC 1:100-1:200FC 1:50-1:100ELISA 1:10000 |
| Storage Instruction: | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
| Gene Symbol: | NCAM1 |
| Gene ID: | 4684 |
| Uniprot ID: | NCAM1_HUMAN |
| Immunogen: | Purified recombinant fragment of human NCAM1 expressed in E. Coli. |
| Post Translational Modifications | Polysialylated at Asn-459 and Asn-488 by ST8SIA2 and ST8SIA4. Polysialylation modulates cell interactions by confering both attractive and repulsive properties that are highly regulated by ST8SIA2 and ST8SIA4. Polysialylation is formed on a-2,3-linked sialic acid of core glycans. |
| Function | This protein is a cell adhesion molecule involved in neuron-neuron adhesion, neurite fasciculation, outgrowth of neurites, etc. (Microbial infection) Acts as a receptor for rabies virus. (Microbial infection) Acts as a receptor for Zika virus. |
| Protein Name | Neural Cell Adhesion Molecule 1N-Cam-1Ncam-1Cd Antigen Cd56 |
| Database Links | Reactome: R-HSA-3000178Reactome: R-HSA-375165Reactome: R-HSA-419037Reactome: R-HSA-445144Reactome: R-HSA-5673001Reactome: R-HSA-877300 |
| Cellular Localisation | Isoform 1: Cell MembraneSingle-Pass Type I Membrane ProteinIsoform 2: Cell MembraneIsoform 3: Cell MembraneLipid-AnchorGpi-AnchorIsoform 4: Cell MembraneIsoform 5: SecretedIsoform 6: Secreted |
| Alternative Antibody Names | Anti-Neural Cell Adhesion Molecule 1 antibodyAnti-N-Cam-1 antibodyAnti-Ncam-1 antibodyAnti-Cd Antigen Cd56 antibodyAnti-NCAM1 antibodyAnti-NCAM antibody |
Information sourced from Uniprot.org
![Anti-NCAM1 antibody [SM5149] (STJA0005149)](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/600x533/products/180200/403641/STJA0005149_1__19957.1738950646.png?c=1 "Anti-NCAM1 antibody [SM5149] (STJA0005149)")
