| Short Description : | Mouse monoclonal anti-CD56 for use in FC, IP, IHC-P and ICC in Non-Human Primates and Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | FC/IP/IHC-P/ICC |
| Host: | Mouse |
| Reactivity: | Non-Human Primates/Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Monoclonal |
| Clone ID : | MEM-188 |
| Isotype: | IgG2a |
| Conjugation: | Unconjugated |
| Concentration: | 1 mg/mL |
| Formulation: | Phosphate buffered saline (PBS) solution with 15 mM sodium azide |
| Storage Instruction: | Store at 2-8°C for up to 1-year, upon receipt. |
| Immunogen: | KG-1 human acute myelogenous leukemia cell line |
| Background | CD56 (NCAM, neural cell adhesion molecule) is a transmembrane glycoprotein of immunoglobulin family serving as adhesive molecule which is ubiquitously expressed in nervous system, usually as 120 kDa, 140 kDa or 180 kDa isoform, and it is also found on T cells and NK cells. Polysialic modification results in reduction of CD56-mediated cell adhesion and is involved in cell migration, axonal growth, pathfinding and synaptic plasticity. CD56 is a widely used neuroendocrine marker with a high sensitivity for neuroendocrine tumours and ovarian granulosa cell tumours. |
Information sourced from Uniprot.org

