• Immunofluorescence analysis of A549 cells, using AIBP Antibody. The picture on the right is blocked with the synthesized peptide.
  • Western blot analysis of lysates from HeLa cells, using AIBP Antibody. The lane on the right is blocked with the synthesized peptide.
  • Western blot analysis of various cells using AI-BP Polyclonal Antibody diluted at 1：2000

Anti-NAXE antibody (121-170 aa) (STJ91512)

SKU:
STJ91512

£46.00 - £226.00
Current Stock:
Host: Rabbit
Applications: WB/IF/ELISA
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-NADPH-hydrate epimeraseHX epimerase (121-170 aa) is suitable for use in Western Blot, Immunofluorescence and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-1:2000
IF 1:200-1:1000
ELISA 1:40000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: NAXE
Gene ID: 128240
Uniprot ID: NNRE_HUMAN
Immunogen Region: 121-170 aa
Specificity: AI-BP Polyclonal Antibody detects endogenous levels of AI-BP protein.
Immunogen: The antiserum was produced against synthesized peptide derived from the human AIBP at the amino acid range 121-170
Post Translational Modifications Undergoes physiological phosphorylation during sperm capacitation, downstream to PKA activation.
Function Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX. Accelerates cholesterol efflux from endothelial cells to high-density lipoprotein (HDL) and thereby regulates angiogenesis.
Protein Name Nad(Ph-Hydrate Epimerase
Apolipoprotein A-I-Binding Protein
Ai-Bp
Nad(Phx Epimerase
Yjef N-Terminal Domain-Containing Protein 1
Yjef_n1
Database Links Reactome: R-HSA-197264
Cellular Localisation Mitochondrion
Secreted
In Sperm
Secretion Gradually Increases During Capacitation
Alternative Antibody Names Anti-Nad(Ph-Hydrate Epimerase antibody
Anti-Apolipoprotein A-I-Binding Protein antibody
Anti-Ai-Bp antibody
Anti-Nad(Phx Epimerase antibody
Anti-Yjef N-Terminal Domain-Containing Protein 1 antibody
Anti-Yjef_n1 antibody
Anti-NAXE antibody
Anti-AIBP antibody
Anti-APOA1BP antibody
Anti-YJEFN1 antibody

Information sourced from Uniprot.org

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