| Host: | Rabbit |
| Applications: | WB/IHC-P/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000IHC-P:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | NAT2 |
| Gene ID: | 10 |
| Uniprot ID: | ARY2_HUMAN |
| Immunogen Region: | 171-290 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 171-290 of human NAT2 (NP_000006.2). |
| Immunogen Sequence: | TNKEFLNSHLLPKKKHQKIY LFTLEPRTIEDFESMNTYLQ TSPTSSFITTSFCSLQTPEG VYCLVGFILTYRKFNYKDNT DLVEFKTLTEEEVEEVLRNI FKISLGRNLVPKPGDGSLTI |
| Function | Catalyzes the N- or O-acetylation of various arylamine and heterocyclic amine substrates. Participates in the detoxification of a plethora of hydrazine and arylamine drugs, and is able to bioactivate several known carcinogens. |
| Protein Name | Arylamine N-Acetyltransferase 2Arylamide Acetylase 2N-Acetyltransferase Type 2Nat-2N-Hydroxyarylamine O-AcetyltransferasePolymorphic Arylamine N-AcetyltransferasePnat |
| Database Links | Reactome: R-HSA-156582Reactome: R-HSA-9753281 |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-Arylamine N-Acetyltransferase 2 antibodyAnti-Arylamide Acetylase 2 antibodyAnti-N-Acetyltransferase Type 2 antibodyAnti-Nat-2 antibodyAnti-N-Hydroxyarylamine O-Acetyltransferase antibodyAnti-Polymorphic Arylamine N-Acetyltransferase antibodyAnti-Pnat antibodyAnti-NAT2 antibodyAnti-AAC2 antibody |
Information sourced from Uniprot.org