| Short Description : | Rabbit polyclonal NARS (309-548) antibody for use in WB and ELISA in human and mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/ELISA |
| Host: | Rabbit |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | Lot specific |
| Purification: | Affinity purification |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | NARS1 |
| Gene ID: | 4677 |
| Uniprot ID: | SYNC_HUMAN |
| Immunogen Region: | 309-548 |
| Immunogen Sequence: | PALGDVFCIAQSYRAEQSRT RRHLAEYTHVEAECPFLTFD DLLNRLEDLVCDVVDRILKS PAGSIVHELNPNFQPPKRPF KRMNYSDAIVWLKEHDVKKE DGTFYEFGEDIPEAPERLMT DTINEPILLCRFPVEIKSFY MQRCPEDSRLTESVDVLMPN VGEIVGGSMRIFDSEEILAG YKREGIDPTPYYWYTDQRKY GTCPHGGYGLGLERFLTWIL NRYHIRDVCLYPRFVQRCT |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 309-548 of human NARS (NP_004530.1). |
| Function | Catalyzes the attachment of asparagine to tRNA(Asn) in a two-step reaction: asparagine is first activated by ATP to form Asn-AMP and then transferred to the acceptor end of tRNA(Asn). In addition to its essential role in protein synthesis, acts as a signaling molecule that induced migration of CCR3-expressing cells. Has an essential role in the development of the cerebral cortex, being required for proper proliferation of radial glial cells. |
| Protein Name | Asparagine--Trna Ligase - CytoplasmicAsparaginyl-Trna SynthetaseAsnrsAsparaginyl-Trna Synthetase 1 |
| Database Links | Reactome: R-HSA-379716 |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-Asparagine--Trna Ligase - Cytoplasmic antibodyAnti-Asparaginyl-Trna Synthetase antibodyAnti-Asnrs antibodyAnti-Asparaginyl-Trna Synthetase 1 antibodyAnti-NARS1 antibodyAnti-NARS antibodyAnti-NRS antibody |
Information sourced from Uniprot.org
