| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-NARS (309-548) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
NARS1 |
| Gene ID: |
4677 |
| Uniprot ID: |
SYNC_HUMAN |
| Immunogen Region: |
309-548 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 309-548 of human NARS (NP_004530.1). |
| Immunogen Sequence: |
PALGDVFCIAQSYRAEQSRT RRHLAEYTHVEAECPFLTFD DLLNRLEDLVCDVVDRILKS PAGSIVHELNPNFQPPKRPF KRMNYSDAIVWLKEHDVKKE DGTFYEFGEDIPEAPERLMT DTINEPILLCRFPVEIKSFY MQRCPEDSRLTESVDVLMPN VGEIVGGSMRIFDSEEILAG YKREGIDPTPYYWYTDQRKY GTCPHGGYGLGLERFLTWIL NRYHIRDVCLYPRFVQRCT |
| Function | Catalyzes the attachment of asparagine to tRNA(Asn) in a two-step reaction: asparagine is first activated by ATP to form Asn-AMP and then transferred to the acceptor end of tRNA(Asn). In addition to its essential role in protein synthesis, acts as a signaling molecule that induced migration of CCR3-expressing cells. Has an essential role in the development of the cerebral cortex, being required for proper proliferation of radial glial cells. |
| Protein Name | Asparagine--Trna Ligase - CytoplasmicAsparaginyl-Trna SynthetaseAsnrsAsparaginyl-Trna Synthetase 1 |
| Database Links | Reactome: R-HSA-379716 |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-Asparagine--Trna Ligase - Cytoplasmic antibodyAnti-Asparaginyl-Trna Synthetase antibodyAnti-Asnrs antibodyAnti-Asparaginyl-Trna Synthetase 1 antibodyAnti-NARS1 antibodyAnti-NARS antibodyAnti-NRS antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
