Host: | Mouse |
Applications: | IHC-P |
Reactivity: | Human |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description : | Mouse monoclonal antibody anti-Napsin is suitable for use in Immunohistochemistry research applications. |
Clonality : | Monoclonal |
Clone ID : | IP64 |
Conjugation: | Unconjugated |
Isotype: | IgG2b |
Formulation: | Tissue culture supernatant with sodium azide |
Concentration: | >=8.3 mg/L |
Dilution Range: | IHC-P 1:400 |
Storage Instruction: | Store at 2-8°C upon receipt. |
Immunogen: | Prokaryotic recombinant protein corresponding to 126 amino acids of the Napsin A protein. |
Background | Napsin A has a specific function in normal alveolar epithelium and is proposed to play a role in the proteolytic processing of surfactant precursors. Napsin A is reported to be predominantly expressed in lamellar bodies of type II pneumocytes, secondary lysosomes of alveolar macrophages, respiratory epithelium of terminal and respiratory bronchioles, plasma cells, within a subset of lymphocytes in normal lung, as well as in epithelial cells of renal tubules in normal kidney and is weakly expressed in normal spleen. Studies have reported that Napsin A is expressed in 90% of primary lung adenocarcinomas. |
Information sourced from Uniprot.org