| Host: | Goat |
| Applications: | Pep-ELISA/WB |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Goat polyclonal antibody anti-NANOS1 (C-Term) is suitable for use in ELISA and Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Purification: | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Concentration: | 0.5 mg/mL |
| Dilution Range: | Peptide ELISA: antibody detection limit dilution 1:64000.WB: Approx 35-37kDa band observed in Human Testis lysates (calculated MW of 30.2kDa according to NP_955631.1). The observed molecular weight corresponds to earlier findings in literature w |
| Storage Instruction: | Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: | NANOS1 |
| Gene ID: | 340719 |
| Uniprot ID: | NANO1_HUMAN |
| Immunogen Region: | C-Term |
| Accession Number: | NP_955631.1 |
| Immunogen Sequence: | SARDGPPGKKLR |
| Function | May act as a translational repressor which regulates translation of specific mRNAs by forming a complex with PUM2 that associates with the 3'-UTR of mRNA targets. Capable of interfering with the proadhesive and anti-invasive functions of E-cadherin. Up-regulates the production of MMP14 to promote tumor cell invasion. |
| Protein Name | Nanos Homolog 1Nos-1Ec_rep1a |
| Cellular Localisation | CytoplasmPerinuclear RegionColocalizes With Snapin And Pum2 In The Perinuclear Region Of Germ Cells |
| Alternative Antibody Names | Anti-Nanos Homolog 1 antibodyAnti-Nos-1 antibodyAnti-Ec_rep1a antibodyAnti-NANOS1 antibodyAnti-NOS1 antibody |
Information sourced from Uniprot.org