Western blot analysis of lysates from wild type (WT) and 293T cells transfected with NAGS Rabbit pAb, using NAGS Rabbit polyclonal antibody (STJ11105416) at 1:2000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 10s.

Anti-NAGS antibody (STJ11105416)

SKU:
STJ11105416
£112.50 - £524.50
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Host: Rabbit
Applications: WB/ELISA
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3.
Purification: Affinity purification
Concentration: Lot specific
Dilution Range: WB:1:500-1:2000
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: NAGS
Gene ID: 162417
Uniprot ID: NAGS_HUMAN
Specificity: Recombinant protein of human NAGS.
Tissue Specificity Highly expressed in the adult liver, kidney and small intestine. Weakly expressed in the fetal liver, lung, pancreas, placenta, heart and brain tissue.
Post Translational Modifications Probably processed by mitochondrial processing peptidase (MPP). The long form has not yet been isolated.
Function Plays a role in the regulation of ureagenesis by producing the essential cofactor N-acetylglutamate (NAG), thus modulating carbamoylphosphate synthase I (CPS1) activity.
Protein Name N-Acetylglutamate Synthase - Mitochondrial
Amino-Acid Acetyltransferase Cleaved Into - N-Acetylglutamate Synthase Long Form - N-Acetylglutamate Synthase Short Form - N-Acetylglutamate Synthase Conserved Domain Form
Database Links Reactome: R-HSA-70635
Cellular Localisation Mitochondrion Matrix
Alternative Antibody Names Anti-N-Acetylglutamate Synthase - Mitochondrial antibody
Anti-Amino-Acid Acetyltransferase Cleaved Into - N-Acetylglutamate Synthase Long Form - N-Acetylglutamate Synthase Short Form - N-Acetylglutamate Synthase Conserved Domain Form antibody
Anti-NAGS antibody

Information sourced from Uniprot.org

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