Host: |
Rabbit |
Applications: |
WB |
Reactivity: |
Human/Mouse |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-N-Acetylglutamate Synthase-Mitochondrial is suitable for use in Western Blot research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
PBS with 0.05% Proclin300, 50% Glycerol, pH7.3. |
Purification: |
Affinity purification |
Dilution Range: |
WB 1:500-1:2000 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
NAGS |
Gene ID: |
162417 |
Uniprot ID: |
NAGS_HUMAN |
Immunogen: |
Recombinant protein of human NAGS. |
Tissue Specificity | Highly expressed in the adult liver, kidney and small intestine. Weakly expressed in the fetal liver, lung, pancreas, placenta, heart and brain tissue. |
Post Translational Modifications | Probably processed by mitochondrial processing peptidase (MPP). The long form has not yet been isolated. |
Function | Plays a role in the regulation of ureagenesis by producing the essential cofactor N-acetylglutamate (NAG), thus modulating carbamoylphosphate synthase I (CPS1) activity. |
Protein Name | N-Acetylglutamate Synthase - MitochondrialAmino-Acid Acetyltransferase Cleaved Into - N-Acetylglutamate Synthase Long Form - N-Acetylglutamate Synthase Short Form - N-Acetylglutamate Synthase Conserved Domain Form |
Database Links | Reactome: R-HSA-70635 |
Cellular Localisation | Mitochondrion Matrix |
Alternative Antibody Names | Anti-N-Acetylglutamate Synthase - Mitochondrial antibodyAnti-Amino-Acid Acetyltransferase Cleaved Into - N-Acetylglutamate Synthase Long Form - N-Acetylglutamate Synthase Short Form - N-Acetylglutamate Synthase Conserved Domain Form antibodyAnti-NAGS antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance