Anti-NAGS antibody (361-411 aa) (STJ195204)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the human NAGS at the amino acid range 361-411
General Information
| Short Description | Rabbit polyclonal anti-N-acetylglutamate synthase, mitochondrial (361-411 aa) for use in WB and IHC in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000IHC-P 1:50-300 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | NAGS |
| Gene ID | 162417 |
| Uniprot ID | NAGS_HUMAN |
| Immunogen | Synthesized peptide derived from the human NAGS at the amino acid range 361-411 |
| Immunogen Region | 361-411 aa |
| Specificity | This antibody detects endogenous levels of NAGS at Human/Mouse |
Additional Info
| Post Translational Modifications | Probably processed by mitochondrial processing peptidase (MPP). The long form has not yet been isolated. |
| Function | Plays a role in the regulation of ureagenesis by producing the essential cofactor N-acetylglutamate (NAG), thus modulating carbamoylphosphate synthase I (CPS1) activity. |
| Protein Name | N-Acetylglutamate Synthase - MitochondrialAmino-Acid Acetyltransferase Cleaved Into - N-Acetylglutamate Synthase Long Form - N-Acetylglutamate Synthase Short Form - N-Acetylglutamate Synthase Conserved Domain Form |
| Database Links | Reactome: R-HSA-70635 |
| Cellular Localisation | Mitochondrion Matrix |
| Alternative Antibody Names | Anti-N-Acetylglutamate Synthase - Mitochondrial antibodyAnti-Amino-Acid Acetyltransferase Cleaved Into - N-Acetylglutamate Synthase Long Form - N-Acetylglutamate Synthase Short Form - N-Acetylglutamate Synthase Conserved Domain Form antibodyAnti-NAGS antibody |
Information sourced from Uniprot.org