| Host: |
Rabbit |
| Applications: |
IHC/ELISA |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Soss Complex Subunit B2 is suitable for use in Immunohistochemistry and ELISA research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4 |
| Purification: |
Antigen affinity purification |
| Concentration: |
0.9 mg/mL |
| Dilution Range: |
IHC 1:50-1:200 |
| Storage Instruction: |
Store at-20°C for long term, and avoid freeze-thaw cycles. |
| Function | Component of the SOSS complex, a multiprotein complex that functions downstream of the MRN complex to promote DNA repair and G2/M checkpoint. In the SOSS complex, acts as a sensor of single-stranded DNA that binds to single-stranded DNA, in particular to polypyrimidines. The SOSS complex associates with DNA lesions and influences diverse endpoints in the cellular DNA damage response including cell-cycle checkpoint activation, recombinational repair and maintenance of genomic stability. Required for efficient homologous recombination-dependent repair of double-strand breaks (DSBs) and ATM-dependent signaling pathways. |
| Protein Name | Soss Complex Subunit B2Nucleic Acid-Binding Protein 1Oligonucleotide/Oligosaccharide-Binding Fold-Containing Protein 2aSensor Of Single-Strand Dna Complex Subunit B2Sensor Of Ssdna Subunit B2Soss-B2Single-Stranded Dna-Binding Protein 2Hssb2 |
| Database Links | Reactome: R-HSA-6807505 |
| Cellular Localisation | NucleusLocalizes To Nuclear Foci Following Dna Damage |
| Alternative Antibody Names | Anti-Soss Complex Subunit B2 antibodyAnti-Nucleic Acid-Binding Protein 1 antibodyAnti-Oligonucleotide/Oligosaccharide-Binding Fold-Containing Protein 2a antibodyAnti-Sensor Of Single-Strand Dna Complex Subunit B2 antibodyAnti-Sensor Of Ssdna Subunit B2 antibodyAnti-Soss-B2 antibodyAnti-Single-Stranded Dna-Binding Protein 2 antibodyAnti-Hssb2 antibodyAnti-NABP1 antibodyAnti-OBFC2A antibodyAnti-SSB2 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
