Anti-NAB2 antibody [EBS-T-005] (STJ16101075)

SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgG1k
ImmunogenA BALB/c mouse was immunized with partial recombinant NAB2. Fusion partner: Sp2/0.
STJ16101075
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General Information

Short DescriptionMouse monoclonal anti-NGFI-A-binding protein 2 for use in IHC in Human samples. Datasheet included with dilution recommendations, and related reagents.
ApplicationsIHC
HostMouse
ReactivityHuman
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

ClonalityMonoclonal
Clone IDEBS-T-005
IsotypeIgG1k
ConjugationUnconjugated
ConcentrationCan be provided as 100 ยตg/mL, 500 ยตg/mL or 1mg/mL.
PurificationAffinity purified from tissue culture.
Dilution RangeImmunohistology (1-2 ยตg/ml for 30 minutes at RT).
FormulationPBS with 0.02% Sodium Azide.
Storage InstructionStore for up to 1 year at 2-8ยฐC upon receipt.

Target Information

Gene SymbolNAB2
Gene ID4665
Uniprot IDNAB2_HUMAN
ImmunogenA BALB/c mouse was immunized with partial recombinant NAB2. Fusion partner: Sp2/0.

Additional Info

Tissue Specificity Widely expressed at low levels. Highly expressed in melanoma cell lines.
Post Translational Modifications Sumoylation by EGR2 represses EGR2 transcriptional activity in hindbrain.
Function Acts as a transcriptional repressor for zinc finger transcription factors EGR1 and EGR2. Isoform 2 lacks repression ability.
Protein Name Ngfi-A-Binding Protein 2
Egr-1-Binding Protein 2
Melanoma-Associated Delayed Early Response Protein
Protein Mader
Database Links Reactome: R-HSA-9031628
Reactome: R-HSA-9619665
Cellular Localisation Nucleus
Isoform 2 Is Not Localized To The Nucleus
Alternative Antibody Names Anti-Ngfi-A-Binding Protein 2 antibody
Anti-Egr-1-Binding Protein 2 antibody
Anti-Melanoma-Associated Delayed Early Response Protein antibody
Anti-Protein Mader antibody
Anti-NAB2 antibody
Anti-MADER antibody

Information sourced from Uniprot.org

Citations

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