![Anti-NAB2 antibody [EBS-T-005] (STJ16101075)](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/124x110/products/149791/302542/STJ16101075_1__70132.1646940696.jpg?c=1 "Anti-NAB2 antibody [EBS-T-005] (STJ16101075)")
![Anti-NAB2 antibody [EBS-T-005] (STJ16101075)](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/1280x1280/products/149791/302542/STJ16101075_1__70132.1646940696.jpg?c=1 "Anti-NAB2 antibody [EBS-T-005] (STJ16101075)")
| Short Description : | Mouse monoclonal anti-NGFI-A-binding protein 2 for use in IHC in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | IHC |
| Host: | Mouse |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Monoclonal |
| Clone ID : | EBS-T-005 |
| Isotype: | IgG1k |
| Conjugation: | Unconjugated |
| Concentration: | Can be provided as 100 µg/mL, 500 µg/mL or 1mg/mL. |
| Purification: | Affinity purified from tissue culture. |
| Dilution Range: | Immunohistology (1-2 µg/ml for 30 minutes at RT). |
| Formulation: | PBS with 0.02% Sodium Azide. |
| Storage Instruction: | Store for up to 1 year at 2-8°C upon receipt. |
| Gene Symbol: | NAB2 |
| Gene ID: | 4665 |
| Uniprot ID: | NAB2_HUMAN |
| Immunogen: | A BALB/c mouse was immunized with partial recombinant NAB2. Fusion partner: Sp2/0. |
| Tissue Specificity | Widely expressed at low levels. Highly expressed in melanoma cell lines. |
| Post Translational Modifications | Sumoylation by EGR2 represses EGR2 transcriptional activity in hindbrain. |
| Function | Acts as a transcriptional repressor for zinc finger transcription factors EGR1 and EGR2. Isoform 2 lacks repression ability. |
| Protein Name | Ngfi-A-Binding Protein 2Egr-1-Binding Protein 2Melanoma-Associated Delayed Early Response ProteinProtein Mader |
| Database Links | Reactome: R-HSA-9031628Reactome: R-HSA-9619665 |
| Cellular Localisation | NucleusIsoform 2 Is Not Localized To The Nucleus |
| Alternative Antibody Names | Anti-Ngfi-A-Binding Protein 2 antibodyAnti-Egr-1-Binding Protein 2 antibodyAnti-Melanoma-Associated Delayed Early Response Protein antibodyAnti-Protein Mader antibodyAnti-NAB2 antibodyAnti-MADER antibody |
Information sourced from Uniprot.org
