• Formalin-fixed, paraffin-embedded human skeletal muscle stained with anti-myoglobin antibody using peroxidase-conjugate and DAB chromogen. Note the cytoplasmic staining of skeletal muscle fibers.

Anti-Myoglobin antibody (Full length) [ZR69] (STJ180527)

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STJ180527

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Host: Rabbit
Applications: IHC-P
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit monoclonal antibody anti-Myoglobin (Full length) is suitable for use in Immunohistochemistry research applications.
Clonality: Monoclonal
Clone ID: ZR69
Conjugation: Unconjugated
Isotype: IgG
Formulation: Tris-HCI buffer containing stabilizing protein (BSA) and <0.1% ProClin
Purification: Affinity purified
Dilution Range: 1:100-200
Storage Instruction: Store at 2‐8°C for up to 24 months. Predilute: Ready to use, no reconstitution necessary. Concentrate: Use dilution range and appropriate lab‐standardized diluent. Stability after dilution: 7 days at 24°C, 3 months at 2‐8°C, 6months at ‐20°C.
Gene Symbol: MB
Gene ID: 4151
Uniprot ID: MYG_HUMAN
Immunogen Region: Full length
Specificity: Positive control: Skeletal muscle
Immunogen: Recombinant human full-length Myoglobin (MB) protein
Function Monomeric heme protein which primary function is to store oxygen and facilitate its diffusion within muscle tissues. Reversibly binds oxygen through a pentacoordinated heme iron and enables its timely and efficient release as needed during periods of heightened demand. Depending on the oxidative conditions of tissues and cells, and in addition to its ability to bind oxygen, it also has a nitrite reductase activity whereby it regulates the production of bioactive nitric oxide. Under stress conditions, like hypoxia and anoxia, it also protects cells against reactive oxygen species thanks to its pseudoperoxidase activity.
Protein Name Myoglobin
Nitrite Reductase Mb
Pseudoperoxidase Mb
Database Links Reactome: R-HSA-8981607
Cellular Localisation Cytoplasm
Sarcoplasm
Alternative Antibody Names Anti-Myoglobin antibody
Anti-Nitrite Reductase Mb antibody
Anti-Pseudoperoxidase Mb antibody
Anti-MB antibody

Information sourced from Uniprot.org

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