| Host: | Mouse |
| Applications: | ELISA/WB |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Mouse monoclonal anti-Myoglobin (1-154aa) for use in ELISA and WB in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Clonality : | Monoclonal |
| Clone ID : | AT6E10 |
| Conjugation: | Unconjugated |
| Isotype: | IgG1k |
| Formulation: | Liquid in phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% Glycerol |
| Purification: | By protein-A affinity chromatography |
| Concentration: | 1 mg/mL |
| Storage Instruction: | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | MB |
| Gene ID: | 4151 |
| Uniprot ID: | MYG_HUMAN |
| Immunogen Region: | 1-154aa |
| Accession Number: | NP_976312 |
| Immunogen: | Recombinant human Myoglobin (1-154aa) purified from E. coli |
| Function | Monomeric heme protein which primary function is to store oxygen and facilitate its diffusion within muscle tissues. Reversibly binds oxygen through a pentacoordinated heme iron and enables its timely and efficient release as needed during periods of heightened demand. Depending on the oxidative conditions of tissues and cells, and in addition to its ability to bind oxygen, it also has a nitrite reductase activity whereby it regulates the production of bioactive nitric oxide. Under stress conditions, like hypoxia and anoxia, it also protects cells against reactive oxygen species thanks to its pseudoperoxidase activity. |
| Protein Name | MyoglobinNitrite Reductase MbPseudoperoxidase Mb |
| Database Links | Reactome: R-HSA-8981607 |
| Cellular Localisation | CytoplasmSarcoplasm |
| Alternative Antibody Names | Anti-Myoglobin antibodyAnti-Nitrite Reductase Mb antibodyAnti-Pseudoperoxidase Mb antibodyAnti-MB antibody |
Information sourced from Uniprot.org