Anti-MYO5A antibody (1784-1833) (STJ94315)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenThe antiserum was produced against synthesized peptide derived from human MYO5A. AA range:1784-1833
General Information
| Short Description | Rabbit polyclonal anti-Unconventional myosin-Va (1784-1833) for use in WB and IHC in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000IHC-p 1:50-300 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | MYO5A |
| Gene ID | 4644 |
| Uniprot ID | MYO5A_HUMAN |
| Immunogen | The antiserum was produced against synthesized peptide derived from human MYO5A. AA range:1784-1833 |
| Immunogen Region | 1784-1833 |
| Specificity | Myosin VA Polyclonal Antibody detects endogenous levels of Myosin VA protein. |
Additional Info
| Tissue Specificity | Detected in melanocytes. |
| Function | Processive actin-based motor that can move in large steps approximating the 36-nm pseudo-repeat of the actin filament. Can hydrolyze ATP in the presence of actin, which is essential for its function as a motor protein. Involved in melanosome transport. Also mediates the transport of vesicles to the plasma membrane. May also be required for some polarization process involved in dendrite formation. |
| Protein Name | Unconventional Myosin-VaDilute Myosin Heavy Chain - Non-MuscleMyosin Heavy Chain 12Myosin-12Myoxin |
| Database Links | Reactome: R-HSA-1445148Reactome: R-HSA-2029482Reactome: R-HSA-264876Reactome: R-HSA-9664422Reactome: R-HSA-9824585 |
| Cellular Localisation | |
| Alternative Antibody Names | Anti-Unconventional Myosin-Va antibodyAnti-Dilute Myosin Heavy Chain - Non-Muscle antibodyAnti-Myosin Heavy Chain 12 antibodyAnti-Myosin-12 antibodyAnti-Myoxin antibodyAnti-MYO5A antibodyAnti-MYH12 antibody |
Information sourced from Uniprot.org