| Host: | Rabbit |
| Applications: | ELISA/IP/WB |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-MYLK2 (200-250) is suitable for use in ELISA, Immunoprecipitation and Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Contains Tris, HCl/Glycine buffer pH 7.4-7.8, 30% Glycerol and 0.5% BSA, along with cryo-protective agents, Hepes, and long-term preservatives (0.02% Sodium Azide). |
| Purification: | Affinity Purified |
| Concentration: | 0.5-1.5 µg/µl |
| Dilution Range: | WB: 1:2, 500-1:5, 000ELISA: 1:50, 000IP: 1:200 |
| Storage Instruction: | Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
| Gene Symbol: | MYLK2 |
| Gene ID: | 85366 |
| Uniprot ID: | MYLK2_HUMAN |
| Immunogen Region: | 200-250 |
| Immunogen: | Synthetic peptide taken within aino acid region 200-250 on human Myosin light chain kinase 2 protein. |
| Tissue Specificity | Heart and skeletal muscles. Increased expression in the apical tissue compared to the interventricular septal tissue. |
| Function | Implicated in the level of global muscle contraction and cardiac function. Phosphorylates a specific serine in the N-terminus of a myosin light chain. |
| Protein Name | Myosin Light Chain Kinase 2 - Skeletal/Cardiac MuscleMlck2 |
| Cellular Localisation | CytoplasmColocalizes With Phosphorylated Myosin Light Chain (Rlcp) At Filaments Of The Myofibrils |
| Alternative Antibody Names | Anti-Myosin Light Chain Kinase 2 - Skeletal/Cardiac Muscle antibodyAnti-Mlck2 antibodyAnti-MYLK2 antibody |
Information sourced from Uniprot.org