| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-MVD (1-270) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
MVD |
| Gene ID: |
4597 |
| Uniprot ID: |
MVD1_HUMAN |
| Immunogen Region: |
1-270 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-270 of human MVD (NP_002452.1). |
| Immunogen Sequence: |
MASEKPLAAVTCTAPVNIAV IKYWGKRDEELVLPINSSLS VTLHQDQLKTTTTAVISKDF TEDRIWLNGREEDVGQPRLQ ACLREIRCLARKRRNSRDGD PLPSSLSCKVHVASVNNFPT AAGLASSAAGYACLAYTLAR VYGVESDLSEVARRGSGSAC RSLYGGFVEWQMGEQADGKD SIARQVAPESHWPELRVLIL VVSAEKKLTGSTVGMRASVE TSPLLRFRAESVVPARMAE |
| Tissue Specificity | Expressed in heart, skeletal muscle, lung, liver, brain, pancreas, kidney and placenta. |
| Function | Catalyzes the ATP dependent decarboxylation of (R)-5-diphosphomevalonate to form isopentenyl diphosphate (IPP). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoids and sterol synthesis. |
| Protein Name | Diphosphomevalonate DecarboxylaseMevalonateDiphosphodecarboxylaseMddaseMevalonate Pyrophosphate Decarboxylase |
| Database Links | Reactome: R-HSA-191273Reactome: R-HSA-2426168Reactome: R-HSA-446199 |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-Diphosphomevalonate Decarboxylase antibodyAnti-Mevalonate antibodyAnti-Diphosphodecarboxylase antibodyAnti-Mddase antibodyAnti-Mevalonate Pyrophosphate Decarboxylase antibodyAnti-MVD antibodyAnti-MPD antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
