| Host: | Rabbit |
| Applications: | WB |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit monoclonal anti-Muscarinic Acetylcholine Receptor M3 for use in WB in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Clonality : | Monoclonal |
| Clone ID : | R05-6Q4 |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Purification: | Affinity Chromatography |
| Dilution Range: | WB 1:500-1:1000 |
| Storage Instruction: | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
| Gene Symbol: | CHRM3 |
| Gene ID: | 1131 |
| Uniprot ID: | ACM3_HUMAN |
| Immunogen: | A synthesized peptide derived from human Muscarinic Acetylcholine Receptor M3 |
| Function | The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is Pi turnover. |
| Protein Name | Muscarinic Acetylcholine Receptor M3 |
| Database Links | Reactome: R-HSA-390648Reactome: R-HSA-399997Reactome: R-HSA-416476 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane ProteinPostsynaptic Cell MembraneBasolateral Cell MembraneEndoplasmic Reticulum MembraneColocalizes With Tmem147 In The Endoplasmic Reticulum (Er) MembraneTmem147 Impairs Its Trafficking To The Cell Membrane Leading To Its Retention In The Er Membrane |
| Alternative Antibody Names | Anti-Muscarinic Acetylcholine Receptor M3 antibodyAnti-CHRM3 antibody |
Information sourced from Uniprot.org