Anti-MUC6 antibody [IHC047] (STJA0042217)

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STJA0042217
£119.50 - £285.50
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Short Description :Mouse monoclonal anti-MUC6 for use in IHC-p in Human samples. Datasheet included with dilution recommendations, and related reagents.
Applications:IHC-p
Host:Mouse
Reactivity:Human
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality :Monoclonal
Clone ID :IHC047
Conjugation:Unconjugated
Formulation:Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide
Storage Instruction:Store at 2-8°C for up to 1 year. Do not freeze.
Gene Symbol:MUC6
Gene ID:4588
Uniprot ID:MUC6_HUMAN
Specificity:Tested and validated on stomach tissue.
Tissue Specificity Expressed in the regenerative zone of gastric antrum, gastric body mucosa and gastric incisura mucosa. Expressed in the deeper mucous glands of gastric antrum. Overexpressed in Helicobacter pylori infected gastric epithelium. Highly expressed in duodenal Brunner's glands, gall bladder, seminal vesicle, pancreatic centroacinar cells and ducts, and periductal glands of the common bile duct.
Post Translational Modifications O-glycosylated.
Function May provide a mechanism for modulation of the composition of the protective mucus layer related to acid secretion or the presence of bacteria and noxious agents in the lumen. Plays an important role in the cytoprotection of epithelial surfaces and are used as tumor markers in a variety of cancers. May play a role in epithelial organogenesis.
Protein Name Mucin-6
Muc-6
Gastric Mucin-6
Database Links Reactome: R-HSA-5083625
Reactome: R-HSA-5083632
Reactome: R-HSA-5083636
Reactome: R-HSA-5621480
Reactome: R-HSA-913709
Reactome: R-HSA-977068
Cellular Localisation Secreted
Alternative Antibody Names Anti-Mucin-6 antibody
Anti-Muc-6 antibody
Anti-Gastric Mucin-6 antibody
Anti-MUC6 antibody

Information sourced from Uniprot.org

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