Anti-MUC20 antibody (STJA0009567)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from human MUC20
General Information
| Short Description | Rabbit polyclonal anti-Mucin-20 for use in WB in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | MUC20 |
| Gene ID | 200958 |
| Uniprot ID | MUC20_HUMAN |
| Immunogen | Synthesized peptide derived from human MUC20 |
| Specificity | This antibody detects endogenous levels of MUC20 at Human, Mouse |
Additional Info
| Function | May regulate MET signaling cascade. Seems to decrease hepatocyte growth factor (HGF)-induced transient MAPK activation. Blocks GRB2 recruitment to MET thus suppressing the GRB2-RAS pathway. Inhibits HGF-induced proliferation of MMP1 and MMP9 expression. |
| Protein Name | Mucin-20Muc-20 |
| Database Links | Reactome: R-HSA-5083625Reactome: R-HSA-5083632Reactome: R-HSA-5083636Reactome: R-HSA-5621480Reactome: R-HSA-8851805Reactome: R-HSA-913709Reactome: R-HSA-977068 |
| Cellular Localisation | SecretedApical Cell MembraneBasolateral Cell MembraneCell ProjectionMicrovillus Membrane |
| Alternative Antibody Names | Anti-Mucin-20 antibodyAnti-Muc-20 antibodyAnti-MUC20 antibodyAnti-KIAA1359 antibodyAnti-UNQ2782 antibodyAnti-PRO7170 antibody |
Information sourced from Uniprot.org