Anti-MUC20 antibody (STJA0009567)

SKU:
STJA0009567

Current Stock:
Host: Rabbit
Applications: WB
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Mucin-20 is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: MUC20
Gene ID: 200958
Uniprot ID: MUC20_HUMAN
Specificity: This antibody detects endogenous levels of MUC20 at Human, Mouse
Immunogen: Synthesized peptide derived from human MUC20
Function May regulate MET signaling cascade. Seems to decrease hepatocyte growth factor (HGF)-induced transient MAPK activation. Blocks GRB2 recruitment to MET thus suppressing the GRB2-RAS pathway. Inhibits HGF-induced proliferation of MMP1 and MMP9 expression.
Protein Name Mucin-20
Muc-20
Database Links Reactome: R-HSA-5083625
Reactome: R-HSA-5083632
Reactome: R-HSA-5083636
Reactome: R-HSA-5621480
Reactome: R-HSA-8851805
Reactome: R-HSA-913709
Reactome: R-HSA-977068
Cellular Localisation Secreted
Apical Cell Membrane
Basolateral Cell Membrane
Cell Projection
Microvillus Membrane
Alternative Antibody Names Anti-Mucin-20 antibody
Anti-Muc-20 antibody
Anti-MUC20 antibody
Anti-KIAA1359 antibody
Anti-UNQ2782 antibody
Anti-PRO7170 antibody

Information sourced from Uniprot.org

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