Anti-MTMR12 antibody (523-573 aa) (STJ196137)

SKU:
STJ196137
$67.62 - $360.18
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Short Description :Rabbit polyclonal anti-Myotubularin-related protein 12 (523-573 aa) for use in WB, ELISA and IHC in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents.
Applications:WB/ELISA/IHC
Host:Rabbit
Reactivity:Human/Mouse/Rat
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality :Polyclonal
Isotype:IgG
Conjugation:Unconjugated
Concentration:1 mg/mL
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Dilution Range:WB 1:500-2000
IHC-P 1:50-300
ELISA 2000-20000
Formulation:Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Storage Instruction:Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol:MTMR12
Gene ID:54545
Uniprot ID:MTMRC_HUMAN
Immunogen:Synthesized peptide derived from the human MTMRC at the amino acid range 523-573
Immunogen Region:523-573 aa
Specificity:This antibody detects endogenous levels of MTMRC at Human/Mouse/Rat
Function Acts as an adapter for the myotubularin-related phosphatases. Regulates phosphatase MTM1 protein stability and possibly its intracellular location. By stabilizing MTM1 protein levels, required for skeletal muscle maintenance but not for myogenesis.
Protein Name Myotubularin-Related Protein 12
Inactive Phosphatidylinositol 3-Phosphatase 12
Phosphatidylinositol 3 Phosphate 3-Phosphatase Adapter Subunit
3-Pap
3-Phosphatase Adapter Protein
Database Links Reactome: R-HSA-1660516
Cellular Localisation Cytoplasm
Sarcoplasmic Reticulum
Myofibril
Sarcomere
Localizes To Punctate Vesicles When Associated With Mtm1
Localizes To Triads
A Structure Formed By A T Tubule And Two Sarcoplasmic Reticulum Terminal Cisterna
In Skeletal Muscles
Co-Localizes With Mtm1 In The Sarcomere
Partially Localizes To The Sarcoplasmic Reticulum In Skeletal Muscles
Alternative Antibody Names Anti-Myotubularin-Related Protein 12 antibody
Anti-Inactive Phosphatidylinositol 3-Phosphatase 12 antibody
Anti-Phosphatidylinositol 3 Phosphate 3-Phosphatase Adapter Subunit antibody
Anti-3-Pap antibody
Anti-3-Phosphatase Adapter Protein antibody
Anti-MTMR12 antibody
Anti-KIAA1682 antibody
Anti-PIP3AP antibody

Information sourced from Uniprot.org