Western blot analysis of lysates from HpeG2 cells, primary antibody was diluted at 1:1000, 4°C over night

Anti-MTMR12 antibody (523-573 aa) (STJ196137)

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STJ196137
£48.00 - £252.00
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Host: Rabbit
Applications: WB/ELISA/IHC
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Rabbit polyclonal antibody anti-Myotubularin-related protein 12 (523-573 aa) is suitable for use in Western Blot, ELISA and Immunohistochemistry research applications.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-2000
IHC-P 1:50-300
ELISA 2000-20000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: MTMR12
Gene ID: 54545
Uniprot ID: MTMRC_HUMAN
Immunogen Region: 523-573 aa
Specificity: This antibody detects endogenous levels of MTMRC at Human/Mouse/Rat
Immunogen: Synthesized peptide derived from the human MTMRC at the amino acid range 523-573
Function Acts as an adapter for the myotubularin-related phosphatases. Regulates phosphatase MTM1 protein stability and possibly its intracellular location. By stabilizing MTM1 protein levels, required for skeletal muscle maintenance but not for myogenesis.
Protein Name Myotubularin-Related Protein 12
Inactive Phosphatidylinositol 3-Phosphatase 12
Phosphatidylinositol 3 Phosphate 3-Phosphatase Adapter Subunit
3-Pap
3-Phosphatase Adapter Protein
Database Links Reactome: R-HSA-1660516
Cellular Localisation Cytoplasm
Sarcoplasmic Reticulum
Myofibril
Sarcomere
Localizes To Punctate Vesicles When Associated With Mtm1
Localizes To Triads
A Structure Formed By A T Tubule And Two Sarcoplasmic Reticulum Terminal Cisterna
In Skeletal Muscles
Co-Localizes With Mtm1 In The Sarcomere
Partially Localizes To The Sarcoplasmic Reticulum In Skeletal Muscles
Alternative Antibody Names Anti-Myotubularin-Related Protein 12 antibody
Anti-Inactive Phosphatidylinositol 3-Phosphatase 12 antibody
Anti-Phosphatidylinositol 3 Phosphate 3-Phosphatase Adapter Subunit antibody
Anti-3-Pap antibody
Anti-3-Phosphatase Adapter Protein antibody
Anti-MTMR12 antibody
Anti-KIAA1682 antibody
Anti-PIP3AP antibody

Information sourced from Uniprot.org

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