| Host: |
Rabbit |
| Applications: |
WB/ELISA/IHC |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Myotubularin-related protein 12 (523-573 aa) is suitable for use in Western Blot, ELISA and Immunohistochemistry research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-2000IHC-P 1:50-300ELISA 2000-20000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
MTMR12 |
| Gene ID: |
54545 |
| Uniprot ID: |
MTMRC_HUMAN |
| Immunogen Region: |
523-573 aa |
| Specificity: |
This antibody detects endogenous levels of MTMRC at Human/Mouse/Rat |
| Immunogen: |
Synthesized peptide derived from the human MTMRC at the amino acid range 523-573 |
| Function | Acts as an adapter for the myotubularin-related phosphatases. Regulates phosphatase MTM1 protein stability and possibly its intracellular location. By stabilizing MTM1 protein levels, required for skeletal muscle maintenance but not for myogenesis. |
| Protein Name | Myotubularin-Related Protein 12Inactive Phosphatidylinositol 3-Phosphatase 12Phosphatidylinositol 3 Phosphate 3-Phosphatase Adapter Subunit3-Pap3-Phosphatase Adapter Protein |
| Database Links | Reactome: R-HSA-1660516 |
| Cellular Localisation | CytoplasmSarcoplasmic ReticulumMyofibrilSarcomereLocalizes To Punctate Vesicles When Associated With Mtm1Localizes To TriadsA Structure Formed By A T Tubule And Two Sarcoplasmic Reticulum Terminal CisternaIn Skeletal MusclesCo-Localizes With Mtm1 In The SarcomerePartially Localizes To The Sarcoplasmic Reticulum In Skeletal Muscles |
| Alternative Antibody Names | Anti-Myotubularin-Related Protein 12 antibodyAnti-Inactive Phosphatidylinositol 3-Phosphatase 12 antibodyAnti-Phosphatidylinositol 3 Phosphate 3-Phosphatase Adapter Subunit antibodyAnti-3-Pap antibodyAnti-3-Phosphatase Adapter Protein antibodyAnti-MTMR12 antibodyAnti-KIAA1682 antibodyAnti-PIP3AP antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
