| Host: | Goat |
| Applications: | Pep-ELISA/WB |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Goat polyclonal antibody anti-MTHFD2L (N-Term) is suitable for use in ELISA and Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Purification: | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Concentration: | 0.5 mg/mL |
| Dilution Range: | Peptide ELISA: antibody detection limit dilution 1:128000.WB: Approx 28kDa band observed in Human Testis lysates (calculated MW of 31.3kDa according to NP_001004346.2). Recommended concentration: 0.1-0.3µg/ml. |
| Storage Instruction: | Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: | MTHFD2L |
| Gene ID: | 441024 |
| Uniprot ID: | MTD2L_HUMAN |
| Immunogen Region: | N-Term |
| Accession Number: | NP_001004346.2 |
| Immunogen Sequence: | KHIQKEIQRGVES |
| Function | Bifunctional mitochondrial folate-interconverting enzyme that has both NAD/NADP-dependent methylenetetrahydrofolate dehydrogenase and methenyltetrahydrofolate cyclohydrolase activities. |
| Protein Name | Bifunctional Methylenetetrahydrofolate Dehydrogenase/Cyclohydrolase 2 - MitochondrialNadp-Dependent Methylenetetrahydrofolate Dehydrogenase 2-Like ProteinMthfd2-Like Includes - Nad-Dependent Methylenetetrahydrofolate Dehydrogenase - Methenyltetrahydrofolate Cyclohydrolase |
| Database Links | Reactome: R-HSA-196757 |
| Cellular Localisation | Mitochondrion Inner MembranePeripheral Membrane ProteinMatrix Side |
| Alternative Antibody Names | Anti-Bifunctional Methylenetetrahydrofolate Dehydrogenase/Cyclohydrolase 2 - Mitochondrial antibodyAnti-Nadp-Dependent Methylenetetrahydrofolate Dehydrogenase 2-Like Protein antibodyAnti-Mthfd2-Like Includes - Nad-Dependent Methylenetetrahydrofolate Dehydrogenase - Methenyltetrahydrofolate Cyclohydrolase antibodyAnti-MTHFD2L antibody |
Information sourced from Uniprot.org