| Host: | Rabbit |
| Applications: | WB |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-S-methyl-5 thioadenosine phosphorylase is suitable for use in Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-2000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | MTAP |
| Gene ID: | 4507 |
| Uniprot ID: | MTAP_HUMAN |
| Specificity: | This antibody detects endogenous levels of MTAP at Human, Mouse |
| Immunogen: | Synthesized peptide derived from human MTAP |
| Function | Catalyzes the reversible phosphorylation of S-methyl-5'-thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates. |
| Protein Name | S-Methyl-5'-Thioadenosine Phosphorylase 5'-Methylthioadenosine Phosphorylase Mta Phosphorylase Mtap Mtapase |
| Database Links | Reactome: R-HSA-1237112 Reactome: R-HSA-8950505 |
| Cellular Localisation | Cytoplasm Nucleus |
| Alternative Antibody Names | Anti-S-Methyl-5'-Thioadenosine Phosphorylase antibody Anti-5'-Methylthioadenosine Phosphorylase antibody Anti-Mta Phosphorylase antibody Anti-Mtap antibody Anti-Mtapase antibody Anti-MTAP antibody Anti-MSAP antibody |
Information sourced from Uniprot.org