• Western blot analysis of extracts of A-549 cells, using MTA3 antibody (STJ24626) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 30s.

Anti-MTA3 antibody (40-330) (STJ24626)

SKU:
STJ24626

£112.50 - £524.50
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Host: Rabbit
Applications: WB/ELISA
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3.
Purification: Affinity purification
Concentration: Lot specific
Dilution Range: WB:1:500-1:2000
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: MTA3
Gene ID: 57504
Uniprot ID: MTA3_HUMAN
Immunogen Region: 40-330
Specificity: Recombinant fusion protein containing a sequence corresponding to amino acids 40-330 of human MTA3 (NP_065795.1).
Immunogen Sequence: AKVVCFYRRRDISNTLIMLA DKHAKEIEEESETTVEADLT DKQKHQLKHRELFLSRQYES LPATHIRGKCSVALLNETES VLSYLDKEDTFFYSLVYDPS LKTLLADKGEIRVGPRYQAD IPEMLLEGESDEREQSKLEV KVWDPNSPLTDRQIDQFLVV ARAVGTFARALDCSSSVRQP SLHMSAAAASRDITLFHAMD TLYRHSYDLSSAISVLVPLG GPVLCRDEMEEWSASEASL
Tissue Specificity Expressed in germinal centers of lymphoid tissues. No expression in nonepithelial cells.
Function Acts as a component of the histone deacetylase NuRD complex which participates in the remodeling of chromatin. Plays a role in maintenance of the normal epithelial architecture through the repression of SNAI1 transcription in a histone deacetylase-dependent manner, and thus the regulation of E-cadherin levels. Contributes to transcriptional repression by BCL6.
Protein Name Metastasis-Associated Protein Mta3
Database Links Reactome: R-HSA-3214815
Reactome: R-HSA-427389
Reactome: R-HSA-73762
Reactome: R-HSA-8943724
Reactome: R-HSA-9679191
Reactome: R-HSA-9843940
Reactome: R-HSA-9844594
Reactome: R-HSA-9845323
Cellular Localisation Nucleus
Cytoplasm
Alternative Antibody Names Anti-Metastasis-Associated Protein Mta3 antibody
Anti-MTA3 antibody
Anti-KIAA1266 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance