| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Gene Symbol: | MT3 |
| Gene ID: | 4504 |
| Uniprot ID: | MT3_HUMAN |
| Immunogen Region: | 1-68 aa |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-68 of human MT3 (NP_005945.1). |
| Immunogen Sequence: | MDPETCPCPSGGSCTCADSC KCEGCKCTSCKKSCCSCCPA ECEKCAKDCVCKGGEAAEAE AEKCSCCQ |
| Tissue Specificity | Abundant in a subset of astrocytes in the normal human brain, but greatly reduced in the Alzheimer disease (AD) brain. |
| Function | Binds heavy metals. Contains three zinc and three copper atoms per polypeptide chain and only a negligible amount of cadmium. Inhibits survival and neurite formation of cortical neurons in vitro. |
| Protein Name | Metallothionein-3Mt-3GifbGifGrowth Inhibitory FactorMetallothionein-IiiMt-Iii |
| Database Links | Reactome: R-HSA-5661231 |
| Alternative Antibody Names | Anti-Metallothionein-3 antibodyAnti-Mt-3 antibodyAnti-Gifb antibodyAnti-Gif antibodyAnti-Growth Inhibitory Factor antibodyAnti-Metallothionein-Iii antibodyAnti-Mt-Iii antibodyAnti-MT3 antibody |
Information sourced from Uniprot.org