Anti-MSR1 antibody (90-274) (STJ24620)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal MSR1 (90-274) antibody for use in WB, IF, ICC and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IF/ICC/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:1000IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.05% Proclin300, 50% Glycerol, pH7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | MSR1 |
| Gene ID | 4481 |
| Uniprot ID | MSRE_HUMAN |
| Immunogen Region | 90-274 |
| Immunogen Sequence | ANDITQSLTGKGNDSEEEMR FQEVFMEHMSNMEKRIQHIL DMEANLMDTEHFQNFSMTTD QRFNDILLQLSTLFSSVQGH GNAIDEISKSLISLNTTLLD LQLNIENLNGKIQENTFKQQ EEISKLEERVYNVSAEIMAM KEEQVHLEQEIKGEVKVLNN ITNDLRLKDWEHSQTLRNIT LIQGP |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 90-274 of human MSR1 (NP_619729.1). |
Additional Info
| Tissue Specificity | Isoform I, isoform II and isoform III are expressed in monocyte-derived macrophages. Isoform I and isoform II are expressed in the liver, placenta and brain. |
| Function | Membrane glycoproteins implicated in the pathologic deposition of cholesterol in arterial walls during atherogenesis. Two types of receptor subunits exist. These receptors mediate the endocytosis of a diverse group of macromolecules, including modified low density lipoproteins (LDL). Isoform III does not internalize acetylated LDL. |
| Protein Name | Macrophage Scavenger Receptor Types I And IiMacrophage Acetylated Ldl Receptor I And IiScavenger Receptor Class A Member 1Cd Antigen Cd204 |
| Database Links | Reactome: R-HSA-3000480 |
| Cellular Localisation | MembraneSingle-Pass Type Ii Membrane Protein |
| Alternative Antibody Names | Anti-Macrophage Scavenger Receptor Types I And Ii antibodyAnti-Macrophage Acetylated Ldl Receptor I And Ii antibodyAnti-Scavenger Receptor Class A Member 1 antibodyAnti-Cd Antigen Cd204 antibodyAnti-MSR1 antibodyAnti-SCARA1 antibody |
Information sourced from Uniprot.org