• Western blot analysis of extracts of various cell lines, using MSR1 antibody (STJ116120) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.

Anti-MSR1 antibody (192-451) (STJ116120)

SKU:
STJ116120

£112.50 - £522.50
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Host: Rabbit
Applications: WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-MSR1 (192-451) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:1000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: MSR1
Gene ID: 4481
Uniprot ID: MSRE_HUMAN
Immunogen Region: 192-451
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 192-451 of human MSR1 (NP_619729.1).
Immunogen Sequence: LNIENLNGKIQENTFKQQEE ISKLEERVYNVSAEIMAMKE EQVHLEQEIKGEVKVLNNIT NDLRLKDWEHSQTLRNITLI QGPPGPPGEKGDRGPTGESG PRGFPGPIGPPGLKGDRGAI GFPGSRGLPGYAGRPGNSGP KGQKGEKGSGNTLTPFTKVR LVGGSGPHEGRVEILHSGQW GTICDDRWEVRVGQVVCRSL GYPGVQAVHKAAHFGQGTGP IWLNEVFCFGRESSIEECK
Tissue Specificity Isoform I, isoform II and isoform III are expressed in monocyte-derived macrophages. Isoform I and isoform II are expressed in the liver, placenta and brain.
Function Membrane glycoproteins implicated in the pathologic deposition of cholesterol in arterial walls during atherogenesis. Two types of receptor subunits exist. These receptors mediate the endocytosis of a diverse group of macromolecules, including modified low density lipoproteins (LDL). Isoform III does not internalize acetylated LDL.
Protein Name Macrophage Scavenger Receptor Types I And Ii
Macrophage Acetylated Ldl Receptor I And Ii
Scavenger Receptor Class A Member 1
Cd Antigen Cd204
Database Links Reactome: R-HSA-3000480
Cellular Localisation Membrane
Single-Pass Type Ii Membrane Protein
Alternative Antibody Names Anti-Macrophage Scavenger Receptor Types I And Ii antibody
Anti-Macrophage Acetylated Ldl Receptor I And Ii antibody
Anti-Scavenger Receptor Class A Member 1 antibody
Anti-Cd Antigen Cd204 antibody
Anti-MSR1 antibody
Anti-SCARA1 antibody

Information sourced from Uniprot.org

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