| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-MSR1 (192-451) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:1000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
MSR1 |
| Gene ID: |
4481 |
| Uniprot ID: |
MSRE_HUMAN |
| Immunogen Region: |
192-451 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 192-451 of human MSR1 (NP_619729.1). |
| Immunogen Sequence: |
LNIENLNGKIQENTFKQQEE ISKLEERVYNVSAEIMAMKE EQVHLEQEIKGEVKVLNNIT NDLRLKDWEHSQTLRNITLI QGPPGPPGEKGDRGPTGESG PRGFPGPIGPPGLKGDRGAI GFPGSRGLPGYAGRPGNSGP KGQKGEKGSGNTLTPFTKVR LVGGSGPHEGRVEILHSGQW GTICDDRWEVRVGQVVCRSL GYPGVQAVHKAAHFGQGTGP IWLNEVFCFGRESSIEECK |
| Tissue Specificity | Isoform I, isoform II and isoform III are expressed in monocyte-derived macrophages. Isoform I and isoform II are expressed in the liver, placenta and brain. |
| Function | Membrane glycoproteins implicated in the pathologic deposition of cholesterol in arterial walls during atherogenesis. Two types of receptor subunits exist. These receptors mediate the endocytosis of a diverse group of macromolecules, including modified low density lipoproteins (LDL). Isoform III does not internalize acetylated LDL. |
| Protein Name | Macrophage Scavenger Receptor Types I And IiMacrophage Acetylated Ldl Receptor I And IiScavenger Receptor Class A Member 1Cd Antigen Cd204 |
| Database Links | Reactome: R-HSA-3000480 |
| Cellular Localisation | MembraneSingle-Pass Type Ii Membrane Protein |
| Alternative Antibody Names | Anti-Macrophage Scavenger Receptor Types I And Ii antibodyAnti-Macrophage Acetylated Ldl Receptor I And Ii antibodyAnti-Scavenger Receptor Class A Member 1 antibodyAnti-Cd Antigen Cd204 antibodyAnti-MSR1 antibodyAnti-SCARA1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
