| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:1000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | MSR1 |
| Gene ID: | 4481 |
| Uniprot ID: | MSRE_HUMAN |
| Immunogen Region: | 192-451 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 192-451 of human MSR1 (NP_619729.1). |
| Immunogen Sequence: | LNIENLNGKIQENTFKQQEE ISKLEERVYNVSAEIMAMKE EQVHLEQEIKGEVKVLNNIT NDLRLKDWEHSQTLRNITLI QGPPGPPGEKGDRGPTGESG PRGFPGPIGPPGLKGDRGAI GFPGSRGLPGYAGRPGNSGP KGQKGEKGSGNTLTPFTKVR LVGGSGPHEGRVEILHSGQW GTICDDRWEVRVGQVVCRSL GYPGVQAVHKAAHFGQGTGP IWLNEVFCFGRESSIEECK |
| Tissue Specificity | Isoform I, isoform II and isoform III are expressed in monocyte-derived macrophages. Isoform I and isoform II are expressed in the liver, placenta and brain. |
| Function | Membrane glycoproteins implicated in the pathologic deposition of cholesterol in arterial walls during atherogenesis. Two types of receptor subunits exist. These receptors mediate the endocytosis of a diverse group of macromolecules, including modified low density lipoproteins (LDL). Isoform III does not internalize acetylated LDL. |
| Protein Name | Macrophage Scavenger Receptor Types I And IiMacrophage Acetylated Ldl Receptor I And IiScavenger Receptor Class A Member 1Cd Antigen Cd204 |
| Database Links | Reactome: R-HSA-3000480 |
| Cellular Localisation | MembraneSingle-Pass Type Ii Membrane Protein |
| Alternative Antibody Names | Anti-Macrophage Scavenger Receptor Types I And Ii antibodyAnti-Macrophage Acetylated Ldl Receptor I And Ii antibodyAnti-Scavenger Receptor Class A Member 1 antibodyAnti-Cd Antigen Cd204 antibodyAnti-MSR1 antibodyAnti-SCARA1 antibody |
Information sourced from Uniprot.org