![Anti-MSLN/Mesothelin nanobody [YE-17] (STJN000589)](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/124x110/products/201202/413300/STJN000589-SDS-PAGE-1__65157.1749232777.jpg?c=1 "Anti-MSLN/Mesothelin nanobody [YE-17] (STJN000589)")
![Anti-MSLN/Mesothelin nanobody [YE-17] (STJN000589)](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/1280x1280/products/201202/413300/STJN000589-SDS-PAGE-1__65157.1749232777.jpg?c=1 "Anti-MSLN/Mesothelin nanobody [YE-17] (STJN000589)")
Anti-MSLN/Mesothelin nanobody [YE-17] (STJN000589)
SPECIFICATIONS
ClonalityMonoclonal
HostAlpaca
ConjugationUnconjugated
IsotypeVHH-8His-Cys-tag
General Information
| Short Description | Alpaca monoclonal nanobody anti-Mesothelin is suitable for use in ELISA and FuncS research applications. |
| Applications | ELISA/FuncS |
| Host | Alpaca |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | YE-17 |
| Isotype | VHH-8His-Cys-tag |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | Purified by Nickel column. |
| Formulation | 0.01M PBS, pH 7.4. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at-20°C 12 months. Store at-80°C long term. |
Target Information
| Gene Symbol | MSLN |
| Gene ID | 10232 |
| Uniprot ID | MSLN_HUMAN |
Additional Info
| Post Translational Modifications | Both MPF and the cleaved form of mesothelin are N-glycosylated. Proteolytically cleaved by a furin-like convertase to generate megakaryocyte-potentiating factor (MPF), and the cleaved form of mesothelin. |
| Function | Membrane-anchored forms may play a role in cellular adhesion. Megakaryocyte-potentiating factor (MPF) potentiates megakaryocyte colony formation in vitro. |
| Protein Name | MesothelinCak1 AntigenPre-Pro-Megakaryocyte-Potentiating Factor Cleaved Into - Megakaryocyte-Potentiating FactorMpf - Mesothelin - Cleaved Form |
| Database Links | Reactome: R-HSA-163125Reactome: R-HSA-381426Reactome: R-HSA-8957275 |
| Cellular Localisation | Cell MembraneLipid-AnchorGpi-AnchorGolgi ApparatusMegakaryocyte-Potentiating Factor: SecretedIsoform 3: Secreted |
| Alternative Nanobody Names | Anti-Mesothelin nanobodyAnti-Cak1 Antigen nanobodyAnti-Pre-Pro-Megakaryocyte-Potentiating Factor Cleaved Into - Megakaryocyte-Potentiating Factor nanobodyAnti-Mpf - Mesothelin - Cleaved Form nanobodyAnti-MSLN nanobodyAnti-MPF nanobody |
Information sourced from Uniprot.org